1067 Sociodemographics, Poor Overall Health, Cardiovascular Disease, Depression, Fatigue, and Daytime Sleepiness Associated With Social Jetlag Independent of Sleep Duration and Insomnia

Abstract

investigated whether reducing the prevalence of insufficient sleep (≤6 hrs.) by 10% or 20% would have a significant impact on attenuating the prevalence of diabetes over a 10-year period. We also explored whether similar observations would be made by increasing the prevalence of individuals engaging in 150 mins/week of moderate physical activity as an alternative to healthy sleep, given the difficulty many have experienced in increasing their habitual sleep time. Results: Based on the simulation model, reducing the prevalence of insufficient sleep by 10% or 20% attenuated the prevalence of diabetes among insufficient sleepers by 1.7% or 2.6%, respectively. By contrast, increasing the prevalence of physical activity by 10% or 20% seemed to be much less impactful. Indeed, the prevalence of diabetes was only reduced by 0.4% or 1.6%, respectively. Conclusion Introduction:Metabolic syndrome poses an increased burden of disease, warranting heightened public health attention. This study assessed effects of birthplace on cardiometabolic profile among blacks with metabolic syndrome and sleep apnea risk, while exploring potential gender-based effects. Methods: This analysis is based on data from 610 black patients (mean age= 63 ± 11 years female=65%) with evidence of metabolic syndrome and were at risk for sleep apnea using the ARES. Participants from four community-based clinics in Brooklyn, NY provided sociodemographic, medical, and clinical data. Clinical data included body mass index (BMI), blood pressure (BP), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and fasting plasma glucose (FPG) or hemoglobin (HbA1c) for those who had a diagnosis of diabetes. General Linear Model (GLM) was used to assess effects of birthplace and gender on cardiometabolic parameters, adjusting for age effects. Results: Of the sample, 61.6 % were foreign-born blacks (FBB) and 38.4 % were US-born blacks (USB Introduction: Sleep problems are frequently reported following a mild traumatic brain injury (mTBI). These problems have yet to be objectively characterized 3 to 12 months post-injury, a timeframe during which symptoms usually subside. At-home actigraphy and a 40 hour sleep deprivation paradigm were used to explore sleep and performance deficits in participants with mTBI compared to healthy controls. Methods: Healthy controls and participants with mTBI in the last 3 to 12 months were recruited (N=15). Sleep data were collected with actigraphy over 14 days as volunteers followed normal at-home routines. In the lab, participants experienced 40 hours of sleep deprivation with subsequent recovery sleep. Psychomotor vigilance task (PVT) responses were collected every four hours in lab while participants were awake and the Match to Sample (M2S) task was administered once a day during baseline, sleep deprivation, and recovery. Results: Based on preliminary descriptive analysis, the mTBI group showed less at-home sleep (< 6 h) than the controls (> 6 h). In addition, the mTBI group showed more variability i...