1079-87 Predictors of 10-year patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: Results from a department of veterans affairs cooperative study

Goldman, Steven; Zadina, Karen; Möritz, Thomas; Ovitt, Theron W.; Sethi, Gulshan K.; Copeland, Jack G.; Thottapurathu, Lizy; Krasnicka, Barbara; Ellis, Nancy; Anderson, R.R.; Henderson, William

doi:10.1016/s0735-1097(04)91163-1

Cited by 77 publications

(111 citation statements)

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“…Larger target vessel size, older age, aspirin use, lower serum cholesterol and better Canadian Cardiovascular Society Functional Class were also associated with higher patency rates. Smoking status and insulinrequiring diabetes were not associated with graft patency (14). More recent reports show that saphenous vein graft occlusion rates have not improved despite our better understanding of its pathophysiology and preventive strategies.…”

Section: Life Expectancy Of Vein Grafts and Risk Factors For Vein Gramentioning

confidence: 90%

See 1 more Smart Citation

Coronary vein graft disease: Pathogenesis and prevention

Parang

Arora

2009

Canadian Journal of Cardiology

155

109

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Section: Life Expectancy Of Vein Grafts and Risk Factors For Vein Gramentioning

confidence: 90%

“…Goldman et al (14) reported data on patency rates of vein grafts from a series of patients who underwent CABG from 1983 to 1988. Patency rates were reported as 95% at one week, 84% at one year, 80% at three years, 69% at six years and 61% at 10 years after the operation.…”

Section: Life Expectancy Of Vein Grafts and Risk Factors For Vein Gramentioning

confidence: 99%

Coronary vein graft disease: Pathogenesis and prevention

Parang

Arora

2009

Canadian Journal of Cardiology

155

109

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“…17,18 Evidence for the use of DAPT after CABG has remained inconclusive. Recently, 2 meta-analysis studies showed that DAPT with aspirin and clopidogrel may improve early SVG patency and clinical outcomes, but not arterial graft patency after CABG.…”

Section: September 9 2014mentioning

confidence: 99%

Impact of Clopidogrel Plus Aspirin Versus Aspirin Alone on the Progression of Native Coronary Artery Disease After Bypass Surgery

et al. 2014

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Background-The effects of dual antiplatelet therapy with aspirin and clopidogrel on the progression of native coronary artery disease after coronary artery bypass grafting are unknown. Methods and Results-In the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) trial, a total of 113 patients were randomized to receive aspirin plus clopidogrel or aspirin plus placebo for 1 year after coronary artery bypass grafting. In this secondary analysis, the 92 patients who underwent preoperative and 1-year postoperative angiograms at 2 centers had each of their coronary stenoses graded serially by using 6 thresholds (grade 0 . We compared the incidence and degree of evolving coronary artery disease between the 2 treatment groups. A total of 543 preoperative stenoses and occlusions were quantified and followed. At 1-year postoperatively, there were 103 evolving (94 worsened, 9 improved) and 22 new lesions. The right coronary artery territory and sites proximal to a graft were more commonly associated with worsening coronary artery disease (P≤0.02). There were no differences in clinical events between treatment groups, and the proportion of patients with evolving or new lesions was also similar (70% versus 74%, aspirin-clopidogrel versus aspirin-placebo, respectively; P=0.8). However, in evolving or new lesions, the mean grade change (1.1±1.0 versus 1.6±1.1, respectively; P=0.01) and the proportion of new occlusions (7% versus 22%; P=0.02) were lower in the aspirin-clopidogrel group. Conclusions-The addition of clopidogrel to aspirin correlates with less worsening of native coronary artery disease 1 year after coronary artery bypass grafting. These findings may help guide post-coronary artery bypass grafting antiplatelet therapy. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00228423.[(Circulation. 2014;130[suppl 1]:S12-S18.)

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“…During this procedure, patients generally receive a left internal mammary artery (LIMA) graft to the left anterior descending coronary artery, and other additional bypasses are constructed using reversed SVGs with aortic anastomoses (12) . The patency of LIMA and other arterial grafts is better than that of saphenous grafts (12) . During the first month after CABG surgery, 3.4% of saphenous graft veins are occluded because of thrombosis, and this is known as early graft vein disease.…”

Section: Discussionmentioning

confidence: 99%

Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?

Sivri¹

2017

Kosuyolu Heart Journal

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Introduction: Circulating monocyte count is a predictive factor of new atherosclerotic plaque development. In addition, there is a strong inverse relationship between high-density lipoprotein (HDL) cholesterol and atherosclerosis. It has been shown that the monocyte/HDL cholesterol ratio (MHR) is a novel inflammatory marker. We aimed to investigate the relationship between MHR and saphenous vein graft disease (SVGD). Patients and Methods:A total of 3 69 patients were divided into 3 groups (positive SVGD group= 150, negative SVGD group= 89, normal coronary artery group= 130). Baseline characteristics and laboratory parameters were recorded and compared among the groups.Results: There were no significant differences between the positive and negative SVGD groups, except for age of SVG and left ventricular ejection fraction, according to baseline characteristics. C-reactive protein (CRP) levels, fasting blood glucose levels and mean platelet volume were higher in the positive SVGD group than in the negative SVGD group (p= 0.008, 0.048 and 0.042, respectively). MHR was not significantly different between the positive and negative SVGD groups (p= 0.169) and normal coronary artery group (p= 0.364). CRP was found to be an independent predictor factor of SVGD. Conclusion:There was no association between MHR and coronary atherosclerosis. MHR was not a predictive factor of SVGD. Bulgular: Bazal karakteristiklere göre SVGD olan ve olmayan gruplarda, SVG yaşı ve sol ventrikül ejeksiyon fraksiyonu haricinde istatistiksel farklılık yoktu. C-reaktif protein, açlık kan şekeri ve ortalama platelet hacmi SVGD olan grupta SVGD olmayan gruba göre daha yüksekti (sırasıyla p değerleri= 0.008, 0.048 ve 0.042). MHR değeri SVGD olan, SVGD olmayan (p= 0.169) ve normal koroner arter grupları (p= 0.364) arasında istatistiksel farklılık göstermedi. CRP, SVGD için bağımsız öngördürücü faktör olarak bulundu.Sonuç: MHR ve koroner ateroskleroz arasında ilişki yoktu. MHR, SVGD için bir öngördürücü faktör değildi.

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1079-87 Predictors of 10-year patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: Results from a department of veterans affairs cooperative study

Cited by 77 publications

References 0 publications

Coronary vein graft disease: Pathogenesis and prevention

Coronary vein graft disease: Pathogenesis and prevention

Impact of Clopidogrel Plus Aspirin Versus Aspirin Alone on the Progression of Native Coronary Artery Disease After Bypass Surgery

Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?

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