1186 Risk Assessment in Newborns Based on the Weight/Length Relationship

Abstract

Posters 586 born infants. Patent ductus arteriosus (PDA) and pharmacological PDA treatment may jeopardize blood flow to the mesenteric vascular bed and therefore, increase risk of NEC. The role of enteral feedings during treatment for PDA is still unclear. The goal is to identify the role of feeding prior to and during the PDA treatment in development of clinical NEC. Methods:The medical charts of infants admitted to the Neonatal Intensive Care Unit with PDA were reviewed to identify demographic, clinical, laboratory data, feeding pattern, ECHO results, and treatment. Data was analyzed in respect to the NEC diagnosis.Results: Among 105 infants diagnosed with PDA , 33 with gestational age less than 30 weeks were included in the analysis. Among those 42.2% were diagnosed with clinical NEC. No difference in gestational age (26.4+/-1.9 vs. 27.0+/-1.7 weeks), birth weight (967+/-314 vs. 1008+/-336 grams), gender, race/ethnicity, maternal steroid use, mode of delivery, umbilical arterial or venal line placement, and pressor use in respect to the NEC were recorded. Majority (78.6% with NEC and 63.2% without, P>0.05) were treated with PGI. Almost all of infants with NEC (90.9%) and without (85.7%) were not on enteral feeding prior to and during PDA treatment. We found no difference in preterm comorbidities but higher median duration of ventilation among infants who were diagnosed with NEC. Conclusion:In very preterm infants with PDA, treatment with PGI and enteral feeding during treatment was not associated with development of NEC. Empirical neonatological experience suggests, that prevalence and degree of neonatal jaundice might be dependent on seasonal variation, mainly due to the sunshine duration. However, evidencebased data on this issue are scarce. Thus, the aim of this study was to provide analysis of differences in the incidence of neonatal hyperbilirubinemia and frequency of phototherapy during summer and winter time. 1185We compared two groups of consecutive healthy, term neonates without AB0 and/or Rh incompatibility born in June (n = 286) and December 2008 (n = 279), respectively.Surprisingly, compared to winter time hyperbilirubinemia >205[U1] umol/l was higher in summer (27.5 vs 22.9%, p-value< 0.05 ). Simultaneously, the freqeuncy of phototherapy was higher during summer (14.3 vs 10.0% , p-value < 0.05).We did not observe any influence of sunshine on the incidence of hyperbilirubinemia of neonates. The main reason for even higher neonatal jaundice during summer month migh be a multifactorial cause of neonatal jaundice, which makes it persistent neonatological challenge. Objective: To check relationship between newborns (NB) classification based on weight/length index (I) and the weight/gestational age adequacy. RISK ASSESSMENT IN NEWBORNS BASEDMethod: A retrospective cross study by record assessment was carried out, where the NB weight (g) was divided by length (cm) for all NB discharged from hospital from September to December, 2009 (N=566). The 10 and 90 percentiles of the indices distribution were calc...