2024
DOI: 10.1101/2024.04.04.588153
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

12/15-Lipoxygenases mediate neuropathic-like pain hypersensitivity in female mice

B Brown,
I Chen,
C Miliano
et al.

Abstract: It is estimated that chronic neuropathic pain conditions exhibit up to 10% prevalence in the general population, with increased incidence in females. However, nonsteroidal inflammatory drugs (NSAIDs) are ineffective, and currently indicated prescription treatments such as opioids, anticonvulsants, and antidepressants provide only limited therapeutic benefit. In the current work, we extended previous studies in male rats utilizing a paradigm of central Toll-like receptor 4 (TLR4)-dependent, NSAID-unresponsive n… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
references
References 74 publications
0
0
0
Order By: Relevance