1229: Racial, Sex, and Geographic Representation in Clinical Studies Supporting the Sepsis Guidelines

Nazer, Lama; Abusara, Aseel; Nabulsi, Hamza; Shapiro, Skyler; Aloran, Batool; Celi, Leo Anthony

doi:10.1097/01.ccm.0000910652.62641.a5

Cited by 2 publications

(2 citation statements)

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“…Globally, access to high-quality, timely sepsis care remains inconsistent and LMICs continue to have the highest death rates. 3,122 The needs and perspectives of these countries are underrepresented in existing sepsis guidelines 123 and many countries lack the infrastructure and human resources to implement recommended best practices. 122 Even within high-income countries, social determinants of health such as race and neighborhood disadvantage may negatively impact survivorship.…”

Section: Survivorship and Global Health Equitymentioning

confidence: 99%

Recovery from Sepsis: Management beyond Acute Care

Andersen,

Herridge,

Fiest

2024

Semin Respir Crit Care Med

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Recovery from sepsis is a key global health issue, impacting 38 million sepsis survivors worldwide per year. Sepsis survivors face a wide range of physical, cognitive, and psychosocial sequelae. Readmissions to hospital following sepsis are an important driver of global healthcare utilization and cost. Family members of sepsis survivors also experience significant stressors related to their role as informal caregivers. Increasing recognition of the burdens of sepsis survivorship has led to the development of postsepsis recovery programs to better support survivors and their families, although optimal models of care remain uncertain. The goal of this article is to perform a narrative review of recovery from sepsis from the perspective of patients, families, and health systems.

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Section: Survivorship and Global Health Equitymentioning

confidence: 99%

Recovery from Sepsis: Management beyond Acute Care

Andersen,

Herridge,

Fiest

2024

Semin Respir Crit Care Med

View full text Add to dashboard Cite

show abstract

“…4,5 Furthermore, trials in the United States predominantly include White patients and individuals with a higher socioeconomic status, which may affect the generalizability of results. [6][7][8] Clinical trials may also underestimate the actual long-term burden of AEs due to incomplete reporting 3 and limited or delayed reporting timelines. RWD in EHRs can provide more comprehensive evidence for drug safety and support a learning health system with real-time AE monitoring, thereby improving cancer treatment outcomes.…”

mentioning

confidence: 99%