1232 Increased Hev Seroprevalence in Patients With Autoimmune Hepatitis

Abstract

Background: Hepatitis E virus (HEV) infection takes a clinically silent, self-limited course in the far majority of cases. Chronic hepatitis E has been reported in some cohorts of immunocompromised individuals. The role of HEV infections in patients with autoimmune hepatitis (AIH) is unknown.

The Asian Pacific Association for the Study of the Liver clinical practice guidance: the diagnosis and management of patients with autoimmune hepatitis

“…Acute HAV infections were higher in treatment-naive pediatric AIH patients. [186], and acute HEV infections were higher in treatment-naive adult AIH patients [187]. For the AIH patient undergoing the conventional immunosuppressive therapy, who has persistent abnormal liver function test results, chronic hepatitis E needs to be excluded, and testing for HEV RNA is recommended [187].…”