13- and 14-membered macrocyclic ligands containing methylcarboxylate or methylphosphonate pendant arms: Chemical and biological evaluation of their 153Sm and 166Ho complexes as potential agents for therapy or bone pain palliation

Lanthanide(III) Complexes of 4,10‐Bis(phosphonomethyl)‐1,4,7,10‐tetraazacyclododecane‐1,7‐diacetic acid (trans‐H6do2a2p) in Solution and in the Solid State: Structural Studies Along the Series

“…The complexes of monophosphorus acid dota derivatives again show biodistributions similar to those of dota complexes. [32,33] Following our previous work on tetraazamacrocycles that bear phosphonate and/or acetate pendant arms, [13][14][15]25,29,[30][31][32][33][34] we have recently reported on the synthesis and characterisation of 1,4,7,10-tetraazacyclododecane-1,7-bis(acetic acid)-4,10-bis(methylenephosphonic acid) (trans-H 6 do2a2p, H 6 L; Scheme 1), on its interaction with 153 …”

Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds

“…In this respect the macrocycles having various donor centres offer exciting possibilities to construct novel supramolecular assemblies that are capable of performing various specific molecular functions [8][9][10][11]. For instance, the precise molecular recognition between these ligands and their guests, mostly transition metal ions or biomolecules such as nucleic acids, proteins provide a good opportunity for studying key aspects of supramolecular chemistry, which are also significant in a variety of disciplines including bioorganic chemistry, biocoordination chemistry, biology, medicine and related science and technology [12][13][14][15][16][17]. Chemically, multi-donor ligands and particularly mixed donor atoms of these ligands are important because of great availability as ligands due to the presence of several potential donor centres and their flexibility to bind with biomolecules or to coordinate with various metal ions.…”

Synthesis, FT-Raman, FT-IR, NMR spectroscopic characterization and antimicrobial activity of new mixed aza-oxo-thia macrocyclic compounds

“…In this respect, the macrocycles having various donor centers offer exciting possibilities to construct novel supramolecular assemblies that are capable of performing various specific molecular functions [10][11][12][13]. For instance, the precise molecular recognition between these compounds and their guests, mostly transition metal ions or biomolecules such as nucleic acids, proteins, provides a good opportunity for studying key aspects of supramolecular chemistry, which are also significant in a variety of disciplines including bioorganic chemistry, biocoordination chemistry, biology, medicine and related science and technology [14][15][16][17][18][19]. Macrocyclic compounds containing amide linkages and their transition metal complexes are found to be biologically interacting materials including antibacterials, antifungals anti-cancers, antibiotics and anti-inflammatory [14,[20][21][22][23].…”