Abstract:Running title: 14-3-3ζ over-expression improves cold tolerance in male mice
AbstractAdaptive thermogenesis, which is partly mediated by sympathetic input on brown adipose tissue (BAT), is a mechanism of heat production in response to prolonged cold that relies upon the actions of Uncoupling Protein-1 (UCP1). Moreover, various stimuli, including norepinephrine and FGF-21, promote the conversion of inguinal white adipocytes to beige adipocytes, which represent a secondary cell type that can contribute to adaptiv… Show more
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