2013
DOI: 10.1016/s0924-9338(13)76448-4
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1410 – Structural brain changes associated with depressive symptoms in elderly with and without mild cognitive impairment

Abstract: IntroductionDepression is common in the elderly with a significant impact on the quality of life, and increased risk for developing dementia. However, the underlying structural brain changes are not well established.ObjectivesTo investigate neuroanatomical correlates of depressive symptoms in elderly people with and without mild cognitive impairment (MCI).Methods621 subjects with (n = 395) and without (n = 226) MCI selected from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database were included in t… Show more

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