162 Specificity of circulating markers for uterine inflammation in pasture-fed, seasonal-calving dairy cows

Spaans, O.K.; Roche, J.R.; Burke, C.R.; Kuhn-Sherlock, B.; Hendriks, S.J.; Hickey, Anthony J. R.; Heiser, Axel; Crookenden, M.A.

doi:10.1016/j.anscip.2023.03.163

Animal - science proceedings

2023

DOI: 10.1016/j.anscip.2023.03.163

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162 Specificity of circulating markers for uterine inflammation in pasture-fed, seasonal-calving dairy cows

O.K. Spaans

J.R. Roche

C.R. Burke

et al.

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2024

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Specificity of 2 peripartum blood markers for early-lactation acute uterine inflammation in pasture-fed, seasonal-calving dairy cows

Spaans,

Roche,

Burke

et al. 2024

JDS Communications

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Graphical Abstract Summary: A common pathogen to the postpartum uterine environment was infused into the uterus of dairy cows to induce a uterine infection at 7 weeks postpartum. A control group received a uterine infusion of saline. As a result, inflammatory pathways were activated, characterized by the increase of uterine polymorphonuclear neutrophils for 2 weeks following the infusion. We selected circulating markers of inflammation, serum amyloid A and alpha-1-acid glycoprotein, to measure in the bacterial and saline infusion groups and identify whether these markers were specific for uterine inflammation. These markers of inflammation were reported in other studies to be elevated early postpartum in dairy cows with a uterine infection. Concentrations of serum amyloid A were elevated in cows that had a uterine infection, inflammation, or both, compared with cows that had no infection or inflammation. There was no difference between groups for alpha-1-acid glycoprotein concentration.

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Specificity of 2 peripartum blood markers for early-lactation acute uterine inflammation in pasture-fed, seasonal-calving dairy cows

Spaans,

Roche,

Burke

et al. 2024

JDS Communications

View full text Add to dashboard Cite

show abstract

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162 Specificity of circulating markers for uterine inflammation in pasture-fed, seasonal-calving dairy cows

Cited by 1 publication

References 1 publication

Specificity of 2 peripartum blood markers for early-lactation acute uterine inflammation in pasture-fed, seasonal-calving dairy cows

Specificity of 2 peripartum blood markers for early-lactation acute uterine inflammation in pasture-fed, seasonal-calving dairy cows

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