164 the Significance of Postnatal Gonadotrophin Surge for Testicular Development in Normal and Cryptorchid Testis

Hadžiselimović, F.; Thommen, L.; Girard, J.

doi:10.1203/00006450-198506000-00184

Pediatr Res

1985

DOI: 10.1203/00006450-198506000-00184

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164 the Significance of Postnatal Gonadotrophin Surge for Testicular Development in Normal and Cryptorchid Testis

F. Hadžiselimović¹,

L. Thommen²,

J. Girard³

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2001

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“…Hormonal surge of LH, FSH and testosterone occurs in all children at the age of 3 months. Many studies have tried to establish the link between this surge and testicular descent (5). De Munich denied the absence of this hormonal surge in cryptorchid children 1, however our study and others 3confirmed the absence of this surge in cryptorchid children.…”

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confidence: 40%

Testicular Descent: When to Interfere?

Hamza

Elrahim²,

Elnagar³

et al. 2001

Eur J Pediatr Surg

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Spontaneous descent of testes after birth can occur in up to 70% of cases, yet the factors contributing to it are still controversial. This study aims to evaluate factors contributing to spontaneous descent of palpable undescended testes. Eighty-four newborns with 126 palpable undescended testes (42 unilateral and 42 bilateral) were followed up for a period of one year to study the occurrence and time of testicular descent and its relation to gestational age, birth weight, uni- or bilaterality and levels of FSH, LH and testosterone. A total of 58 testes (46%) descended between 3 and 6 months. Spontaneous descent occurred in 10 premature patients (14 testes 63%) compared to 44 testes of full-term patients (43%). Descent occurred in 14 unilateral undescended testes (33%) compared to 44 (52%) in bilateral cases. In patients with spontaneous testicular descent there was postnatal peak of LH and testosterone at 2 to 3 months of age which returned to basal level at 6 months of age. In patients with permanent undescended testes the peak of LH and testosterone was very low and almost absent in some of them; no significant difference was found between the mean values of FSH in both groups. No spontaneous testicular descent occurred after the 4th month in the full-term group, whereas in the pre-term group spontaneous descent occurred up to 6 months of age. This study concluded that spontaneous descent of palpable undescended testes is closely related to the presence of LH and testosterone surge. Therapy of undescended testes should start at 4 months of age in a full-term baby and at 6 months of age in a pre-term baby.

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mentioning

confidence: 40%

Testicular Descent: When to Interfere?

Hamza

Elrahim²,

Elnagar³

et al. 2001

Eur J Pediatr Surg

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164 the Significance of Postnatal Gonadotrophin Surge for Testicular Development in Normal and Cryptorchid Testis

Cited by 1 publication

References 0 publications

Testicular Descent: When to Interfere?

Testicular Descent: When to Interfere?

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