1684 Effect of Narasin on nutrient intake and digestibility in wethers fed high-forage diets

Polizel, Daniel Montanher; Westphalen, M. F.; Miszura, Alexandre Arantes; Santos, Marcelo Henrique dos; Silva, R. G.; Bertoloni, Analisa Vasques; Oliveira, Gabriela B; Ferraz, Marcos Vinícius de Castro; Biehl, Marcos Vinícius; Susin, Ivanete; Pires, Alexandre Vaz

doi:10.2527/jam2016-1684

Cited by 6 publications

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“…Corroborating our results, Miszura et al (2019) reported an increase of 7.55% in DMI by adding narasin in high forage-based diets. Conversely, studies reported that inclusion of narasin did not influence forage DMI in animals offered high forage-based diets ( Silva et al, 2015 ; Polizel et al, 2016 ; Pascoalino et al, 2020 ). It should be noted that DMI in the present experiment was not depressed by the inclusion of salinomycin in the diet, despite previous research reporting such outcome in forage- ( Reffett-Stabel et al 1989 ) and feedlot-fed ( Owens et al, 1982 ; Merchen and Berger, 1985 ; Zinn, 1986a ) cattle.…”

Section: Discussionmentioning

confidence: 97%

Effects of supplementation with narasin, salinomycin, or flavomycin on performance and ruminal fermentation characteristics of Bos indicus Nellore cattle fed with forage-based diets

Limede

Marques

Polizel

et al. 2021

Journal of Animal Science

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The aim of the present study was to evaluate the inclusion of narasin, salinomycin, or flavomycin for 140 d on ruminal fermentation parameters, apparent nutrient digestibility, and performance of Nellore cattle offered a forage-based diet. In experiment 1, 32 rumen-cannulated Bos indicus Nellore steers [initial body weight (BW) = 220 ± 12.6 kg] were assigned to individual pens in a randomized complete block design according to their initial shrunk BW. Within block, animals were randomly assigned to 1 of 4 treatments: (1) forage-based diet without feed additives (CON; n = 8), (2) CON diet plus 13 ppm of narasin (NAR; n = 8), (3) CON diet plus 20 ppm of salinomycin (SAL; n = 8), or (4) CON diet plus 3 ppm of flavomycin (FLA; n = 8). The experimental period lasted 140 d and was divided into 5 periods of 28 d each. The inclusion of feed additives did not impact (P ≥ 0.17) dry matter intake (DMI), nutrient intake, and apparent total tract digestibility of nutrients. Nonetheless, steers fed NAR had lower (P < 0.01) molar proportion of acetate compared with CON, SAL, and FLA steers, whereas ruminal acetate tended to be greater (P < 0.09) for SAL vs. CON and FLA, but did not differ (P = 0.68) between CON vs. FLA steers. Ruminal propionate was the highest (P < 0.01) for steers fed NAR and did not differ (P > 0.20) between CON, SAL, and FLA. Consequently, NAR steers had the lowest (P < 0.01) Ac:Pr ratio, whereas Ac:Pr did not differ (P > 0.18) among CON, SAL, and FLA. Total volatile fatty acids were greater (P < 0.04) for NAR and CON vs. SAL and FLA, but did not differ (P > 0.67) among NAR vs. CON and SAL vs. FLA. In experiment 2, 164 Nellore bulls (initial shrunk BW = 299 ± 2.5 kg) were assigned to feedlot pens for 140 d in a randomized complete block design. Within block (n = 10), animals were randomly assigned to the same treatments used in experiment 1. Average daily gain was greater (P < 0.01) in NAR vs. CON, SAL, and FLA bulls, and did not differ (P > 0.12) between CON, SAL, and FLA bulls. Bulls fed NAR had greater (P < 0.02) DMI (as kg/d or % BW) and final shrunk BW compared with CON, SAL, and FLA bulls, whereas DMI and final shrunk BW did not differ (P > 0.26) between CON, SAL, and FLA bulls. Feed efficiency, however, was not impacted (P = 0.51) by any feed additives used herein. Collectively, narasin was the only feed additive that benefited performance and ruminal fermentation of Nellore animals fed a forage-based diet.

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Section: Discussionmentioning

confidence: 97%

Effects of supplementation with narasin, salinomycin, or flavomycin on performance and ruminal fermentation characteristics of Bos indicus Nellore cattle fed with forage-based diets

Limede

Marques

Polizel

et al. 2021

Journal of Animal Science

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“…In agreement with our data, Bell et al (2017a) reported no differences in DM, OM, and NDF digestibility of beef steers receiving a forage-based diet with or without monensin. Moreover, Polizel et al (2016b) reported that narasin supplementation to wethers fed a low-quality high-forage diet did not impact DM and OM digestibility, but NDF digestibility increased as the dose of narasin increased (linear effect). The forage used in the study of Polizel et al (2016b) was lower in quality when compared to the one used herein (6.8 vs. 8.6% CP; 50.4 vs. 70.0% NDF digestibility, respectively) and one might speculate that these differences would likely impact forage intake, rumen retention time, passage rate, and consequently, forage nutrient digestibility.…”

Section: Discussionmentioning

confidence: 99%

Effects of narasin supplementation on dry matter intake and rumen fermentation characteristics of Bos indicus steers fed a high-forage diet

Polizel

Cappellozza

Hoe

et al. 2019

Translational Animal Science

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This study evaluated the effects of narasin on intake and rumen fermentation characteristics of Bos indicus steers offered a high-forage diet for 140 d. On day 0 of the study, 30 rumen-fistulated Nellore steers [initial body weight (BW) = 281 ± 21 kg] were assigned to 30 individual pens in a randomized complete block design according to their initial BW. Animals were randomly assigned to 1 of the 3 treatments: 1) forage-based diet without narasin (CONT; n = 10), 2) CONT diet plus 13 ppm of narasin (13NAR; n = 10), and 3) CONT diet plus 20 ppm of narasin (20NAR; n = 10). The forage used was Tifton-85 (Cynodon dactylon spp.), whereas the carrier for narasin was a 50:50 mixture of soybean hull:corn. The experimental period was divided into 5 periods of 28 d each. Throughout the experimental period, total dry matter intake (DMI) was recorded daily, whereas mineral salt intake was recorded weekly. Blood and ruminal fluid samples were collected on day 0 (prior to treatment feeding), 28, 56, 84, 112, and 140 of the study. Moreover, total tract apparent nutrient digestibility was performed for a 5-d period every 28 d. No treatment effects were observed on forage, mineral, concentrate, or total DMI (P ≥ 0.22). Nonetheless, 13NAR tended to have a greater mineral intake vs. 20NAR cohorts (P = 0.08) Narasin-supplemented animals had reduced rumen acetate, Ac:Pr ratio, as well as greater (P ≤ 0.02) rumen propionate concentrations vs. CONT cohorts. Moreover, 13NAR increased rumen propionate and decreased butyrate, Ac:Pr vs. 20NAR cohorts (P ≤ 0.01). Throughout the experimental period, narasin-supplemented animals had reduced ammonia concentrations vs. CONT cohorts (P < 0.01), whereas no differences were observed between 13NAR and 20NAR (P = 0.80). No treatment or dose effects were observed (P ≥ 0.23) on DM, organic matter (OM), protein, neutral detergent fiber (NDF), acid detergent fiber (ADF), and mineral digestibility. Animals fed 13NAR had a reduced mean plasma urea concentration vs. CONT cohorts (P = 0.03), whereas no further differences were observed (P ≥ 0.12). In summary, narasin supplementation to beef steers offered a high-forage diet did not impact forage, mineral, and total DMI, as well as nutrient digestibility, whereas rumen fermentation characteristics, rumen ammonia, and plasma urea concentrations were positively impacted and lasted throughout the experimental period. Additionally, 13 ppm of narasin resulted in a reduced Ac:Pr ratio and rumen ammonia when compared to animals supplemented with 20 ppm.

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“…Moreover, in an in vitro study, Nagaraja et al (1987) demonstrated that lower doses of narasin resulted in greater rumen propionate concentrations when compared with monensin and lasalocid, as well as being more effective in inhibiting the production of lactic acid than other ionophores and nonionophores compounds. Additionally, Polizel et al (2016a , 2016b ) demonstrated that narasin inclusion into high-forage diets increased total SCFA proportion, as well as NDF and ADF digestibility when compared with the negative control group.…”

Section: Resultsmentioning

confidence: 95%

Effects of supplement type and narasin inclusion on supplement intake by Bos indicus beef bulls grazing a warm-season forage

Cappellozza

Lasmar

Reis

et al. 2018

Translational Animal Science

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This study aimed to evaluate the effects of supplement type and narasin inclusion on the frequency and supplement intake of grazing Bos indicus beef bulls. Four hundred animals were ranked by initial BW (383 ± 35 kg) and allocated into one of four paddocks of Brachiaria brizantha cv. Marandú (100 animals/paddock). Paddocks were randomly assigned to receive either a mineral salt (MIN) or a protein-energetic supplement (PREN) containing or not narasin (N) for a 90-d period. An individual electronic data capture system with 11 feed bunks was used to individually measure supplement intake and meal frequency in each paddock. The evaluations and analysis of individual intake, frequency of visits to the feeder, and intake per visit (I/V) were performed every 15 d and classified as periods (PR1 through PR6). All data were analyzed as a 2 × 2 factorial design with the PROC MIXED procedure of SAS. A supplement type × N × PR interaction was observed (P < 0.0001) for daily supplement intake. No differences were observed between MIN, whereas PREN had a greater (P ≤ 0.03) supplement intake on PR1 and PR3, but a reduced supplement intake on PR6 compared with PREN + N (P = 0.02). Moreover, no supplement type × N interaction (P = 0.47) or N (P = 0.44) effects were observed for daily supplement intake in the present study. A supplement type × N × PR interaction was detected (P < 0.0001) for the frequency of visits in the feeders. Throughout the experimental period, animals from the MIN + N had a greater (P ≤ 0.02) frequency of visits compared with MIN cohorts. A supplement effect was detected for I/V (P = 0.02), whereas neither a narasin effect (P = 0.74) nor interactions (P ≥ 0.16) were observed. Animals offered PREN had a greater I/V when compared with MIN cohorts (145 vs. 846 g/d for MIN and PREN, respectively; SEM = 16.1). When these data are reported as percentage of days visiting the feeder within each PR, MIN and MIN + N animals visited the feeder for 25.8% and 35.9% of the days, respectively. Conversely, no differences were observed (P = 0.65) in the overall mean visits per PR between PREN and PREN + N (12.8 vs. 12.3 d for PREN and PREN + N, respectively; SEM = 0.195). As percentage of days visiting the feeder, PREN and PREN + N visited the feeder for 85.1% and 81.9% of the days, respectively. In summary, narasin inclusion did not reduce supplement intake, regardless of supplement type, but increased the frequency of visits to the feeder for the MIN treatment.

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1684 Effect of Narasin on nutrient intake and digestibility in wethers fed high-forage diets

Cited by 6 publications

References 0 publications

Effects of supplementation with narasin, salinomycin, or flavomycin on performance and ruminal fermentation characteristics of Bos indicus Nellore cattle fed with forage-based diets

Effects of supplementation with narasin, salinomycin, or flavomycin on performance and ruminal fermentation characteristics of Bos indicus Nellore cattle fed with forage-based diets

Effects of narasin supplementation on dry matter intake and rumen fermentation characteristics of Bos indicus steers fed a high-forage diet

Effects of supplement type and narasin inclusion on supplement intake by Bos indicus beef bulls grazing a warm-season forage

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