“…Quality assessment assignments based on the NIH Assessments Measures
ranged from fair [49, 50, 54, 55, 57, 59] to poor
[24, 56], with insufficient data precluding appraisal of one study [58]. Threats to internal validity for
non-randomized control pilots with a fair quality rating included no
justification for sample size [49, 50, 55, 57], measurement of
pre-test outcome measures at one single data point [49], and no objective adherence outcome measures [50].…”