18 F-FDG-PET/CT angiography in the diagnosis of infective endocarditis and cardiac device infection in adult patients with congenital heart disease and prosthetic material

Pizzi, María Nazarena; Dos‐Subirà, Laura; Roque, Albert; Fernández-Hidalgo, Núria; Cuéllar-Calàbria, Hug; Pijuan-Domenech, Antònia; González‐Alujas, M.T.; Subirana-Domènech, Maria Teresa; Miranda, Berta; Ferreira‐González, Ignacio; González-López, Juan José; Igual, A; Maisterra-Santos, Olga; Garcı́a-Dorado, David; Castell‐Conesa, Joan; Almirante, Benito; Amores, Manuel Escobar; Tornos, Pilar; Aguadé-Bruix, Santiago

doi:10.1016/j.ijcard.2017.08.008

Cited by 54 publications

(25 citation statements)

References 26 publications

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“…In addition, our second patient had a 18 F-Fluordeoxyglucose (FDG) Positron Emission Tomography/Computed Tomography Angiography (PET/CTA) myocardial scan which confirmed his diagnosis of endocarditis. This diagnostic tool has been reported to be useful in suspected cases of infectious endocarditis and implantable cardiac electronic device infections [14,15]. To our knowledge, this is the first report of using this diagnostic test in fungal prosthetic valve endocarditis.…”

Section: Discussionmentioning

confidence: 99%

Combination antifungal therapy for treatment of Candida parapsilosis prosthetic valve endocarditis and utility of T2Candida Panel®: A case series

Ahuja

Fong

Louie

2019

IDCases

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Although Candida species are common pathogens for nosocomial infections, Candida endocarditis is still considered a rare entity. Here, we report two cases of Candida parapsilosis endovascular infections in patients with prosthetic valves, both of which responded to combination antifungal therapy without surgical intervention. Additionally, T2 magnetic resonance (T2MR) was used to assess for resolution of invasive candidiasis. The first case is of an elderly man with Candida parapsilosis endovascular infection who responded to combination antifungal therapy with micafungin and fluconazole followed by suppressive therapy, without surgical intervention. The second case is of a middle-aged man with Candida parapsilosis prosthetic valve endocarditis who also responded to combination antifungal therapy with micafungin, flucytosine and fluconazole, without surgical intervention.

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Section: Discussionmentioning

confidence: 99%

Combination antifungal therapy for treatment of Candida parapsilosis prosthetic valve endocarditis and utility of T2Candida Panel®: A case series

Ahuja

Fong

Louie

2019

IDCases

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“…Furthermore, the high sensitivity of FDG PET for diagnosing infections, combined with the high spatial resolution of cardiac CTA, which delineate structural damage, was able to the nine possible cases in PET/nonenhanced CT to be reclassified into eight rejects and one definite case [6]. Moreover, in a study of adult patients with congenital heart disease and suspected IE and/or CIED infection, FDG PET/CTA enhanced the diagnostic sensitivity from 39.1% to 89% and confirmed the diagnosis in 92% of cases [63]. It has been advised that FDG PET/CT is untrustworthy in the 2 months after surgery [64].…”

Section: Imaging Acquisitionmentioning

confidence: 95%

“…Pizzi et al [63] suggested that a combination of FDG PET with CTA could improve the sensitivity in PVE and CIED infection. In their study, they demonstrated that the sensitivity, specificity, PPV, and NPV were 54.5%, 93.8%, 92%, and 60.9% for mDC; 86.4%, 87.5%, 90.2%, and 82.9% for PET/nonenhanced CT; and 91%, 90.6%, 92.8%, and 88.3% for PET/CTA.…”

Section: Imaging Acquisitionmentioning

confidence: 99%

F-18 fluorodeoxyglucose positron emission tomography/computed tomography in the infection of heart

Kong

2021

Yeungnam Univ J Med

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Infections involving the heart are becoming increasingly common, and a timely diagnosis of utmost importance, despite its challenges. F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is a recently introduced diagnostic tool in cardiology. This review focuses on the current evidence for the use of FDG PET/CT in the diagnosis of infective endocarditis, cardiac implantable device infection, left ventricular assist device infection, and secondary complications. The author discuss considerations when using FDG PET/CT in routine clinical practice, patient preparation for reducing physiologic myocardial uptake, acquisition of images, and interpretation of PET/CT findings. This review also functions to highlight the need for a standardized acquisition protocol.

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“…The risk of infective endocarditis (IE) is higher in ACHD patients compared to the general population [73][74][75][76][77][78]. In a study of over 4000 ACHD patients, the incidence of IE was 3%, with the highest rates occurring in patients with unrepaired VSDs, repaired tetralogy of Fallot, and cyanotic heart disease [78].…”

Section: Endocarditismentioning

confidence: 99%

Impact of Non-cardiac Comorbidities in Adults with Congenital Heart Disease: Management of Multisystem Complications

Goldberg

Allan

Learn

2019

Intensive Care of the Adult With Congenital Heart Disease

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18 F-FDG-PET/CT angiography in the diagnosis of infective endocarditis and cardiac device infection in adult patients with congenital heart disease and prosthetic material

Cited by 54 publications

References 26 publications

Combination antifungal therapy for treatment of Candida parapsilosis prosthetic valve endocarditis and utility of T2Candida Panel®: A case series

Combination antifungal therapy for treatment of Candida parapsilosis prosthetic valve endocarditis and utility of T2Candida Panel®: A case series

F-18 fluorodeoxyglucose positron emission tomography/computed tomography in the infection of heart

Impact of Non-cardiac Comorbidities in Adults with Congenital Heart Disease: Management of Multisystem Complications

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