186Incidence of acute kidney injury in patients receiving vancomycin and pipercillin-tazobactam compared to other antibiotic combinations

The combination of vancomycin plus piperacillin-tazobactam increased the odds of acute kidney injury over vancomycin monotherapy, vancomycin plus cefepime or carbapenem, and piperacillin-tazobactam monotherapy. Limited data in critically ill patients suggest the odds of acute kidney injury are increased versus vancomycin monotherapy, and mitigated versus the other comparators. Further research in the critically ill population is needed.

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Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults: A Systematic Review and Meta-Analysis

Luther¹,

Timbrook

Caffrey³

et al. 2018

Critical Care Medicine

197

101

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186Incidence of acute kidney injury in patients receiving vancomycin and pipercillin-tazobactam compared to other antibiotic combinations

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Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults: A Systematic Review and Meta-Analysis

Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults: A Systematic Review and Meta-Analysis

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