2019
DOI: 10.1590/s0004-2803.201900000-02
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18f-FDG Pet/Ct as an Assessment Tool of Hepatocellular Carcinoma Secondary to Non-Alcoholic Fatty Liver Disease Development in Experimental Model

Abstract: BACKGROUND: Hepatocellular carcinoma (HCC) can be the last step of non-alcoholic fatty liver disease (NAFLD) evolution. Experimental models are crucial to elucidate the pathogenesis of HCC secondary to NAFLD. The 2-deoxy-2-(18F)fluoro-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) plays an important role in evaluating HCC development and progression. OBJECTIVE: To standardize the imaging method of PET/CT with 18F-FDG as an evaluation tool of the experimental model of HCC secon… Show more

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“…In recent years, there is an emerging trend in using certain metabolic radiotracers in combination with positron emission tomography/computed tomography (PET/CT) to image tumors and provide prognostic information (Table 1 ). For example, F-18 fluorodeoxyglucose ( 18 F-FDG, an indicator for glycolysis) PET/CT images can be used to non-invasively monitor the development of HCC in a rat model[ 40 ]. Moreover, they are also commonly studied as predictors of overall survival and tumor recurrence after related treatments in HCC[ 41 , 42 ].…”
Section: Metabolism-based Diagnosis and Treatmentmentioning
confidence: 99%
“…In recent years, there is an emerging trend in using certain metabolic radiotracers in combination with positron emission tomography/computed tomography (PET/CT) to image tumors and provide prognostic information (Table 1 ). For example, F-18 fluorodeoxyglucose ( 18 F-FDG, an indicator for glycolysis) PET/CT images can be used to non-invasively monitor the development of HCC in a rat model[ 40 ]. Moreover, they are also commonly studied as predictors of overall survival and tumor recurrence after related treatments in HCC[ 41 , 42 ].…”
Section: Metabolism-based Diagnosis and Treatmentmentioning
confidence: 99%