18F-FDG PET/CT features of pulmonary sclerosing hemangioma

Lee, Eugene; Park, Chang Min; Kang, Keon Wook; Goo, Jin Mo; Kim, Min A; Paeng, Jin Chul; Lee, Hyun Ju; Park, Heae Surng; Chung, Doo Hyun

doi:10.1258/ar.2011.110474

Cited by 31 publications

(30 citation statements)

References 23 publications

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“…PSH has been reported to show various FDG accumulations, with an SUVmax ranging from the background value to 5.3, and the results of the present study were similar to these of previously reported cases (7,(19)(20)(21). FDG PET/CT scan results are usually interpreted as positive for malignancy when the SUVmax of a lung nodule or mass exceeds 2.5 (22).…”

Section: Discussionsupporting

confidence: 90%

“…Lin et al (7) observed that larger PSHs tended to show higher FDG uptake on PET/CT scan. Lee et al (21) reported that the SUVmax was significantly correlated with tumor size in 8 cases of PSH. However, in the present study of 12 PSH cases, there was no significant correlation between the SUVmax and the tumor size.…”

Section: Discussionmentioning

confidence: 99%

“…Chung et al (23) suggested that the presence of a hemangiomatous or papillary component in the tumor may lead to increased FDG uptake. Lee et al (21) attempted to analyze the mechanism or histological influencing factors of the increased FDG uptake of PSH. However, there were no clear histopathological factors influencing SUVmax in the study, including the tumor component, and glucose transporter protein-1 (GLUT-1) and GLUT-4 expression.…”

Section: Discussionmentioning

confidence: 99%

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18F‑FDG PET/CT characteristics of pulmonary sclerosing hemangioma vs. pulmonary hamartoma

et al. 2018

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Abstract. The radiological features of pulmonary sclerosing hemangioma (PSH) and pulmonary hamartoma are poorly specified. Thus, the present study aimed to compare and analyze the characteristics of fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) in PSH versus pulmonary hamartoma.18 F-FDG PET/CT characteristic findings of 12 patients with PSH and 14 patients with pulmonary hamartoma were retrospectively reviewed. A total of 12 lesions were detected from the 12 patients with PSH, of which 3 masses exhibited calcification. The mean diameter and standardized maximum uptake value (SUVmax) were 1.9±0.7 cm and 2.6±1.0, respectively, and there was no significant correlation between the lesion size and SUVmax (P>0.05). For the 14 patients with pulmonary hamartoma, 14 lesions were found, of which 4 exhibited calcification. The mean diameter and SUVmax were 1.7±0.8 cm and 1.5±0.6, respectively, and there was a significant correlation between the size and SUVmax (r= 0.625, r 2 = 0.391, P<0.05). Although there was no significant difference between the size of PSH and pulmonary hamartoma (P>0.05), the SUVmax of PSH was significantly higher than that of pulmonary hamartoma (P<0.05). Moreover, the SUVmax of 1.95 was applied as a cutoff for the diagnosis of PSH, and the resulting sensitivity and specificity for PET/CT to differentiate PSH from pulmonary hamartoma were 83.3 and 78.6%, respectively. Although the morphological features were not specific, PSH showed significantly higher FDG accumulation than pulmonary hamartoma on PET/CT imaging, which may aid the differential diagnosis. Further studies with larger populations are warranted to confirm these study results.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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18F‑FDG PET/CT characteristics of pulmonary sclerosing hemangioma vs. pulmonary hamartoma

et al. 2018

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“…An "air meniscus sign" is frequently observed around the tumour [4]. Although benign, the great majority of sclerosing pneumocytoma present increased uptake on 18 FDG positron emission tomography with standardized uptake values (SUV) that are significantly correlated with tumour size [5].…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Sclerosing Pneumocytoma: Case Report and Review of the Literature

Elizabeth¹,

Edouard²,

Daniel³

2015

J Clin Case Rep

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Aims: Pulmonary sclerosing pneumocytoma is a rare benign neoplastic tumour. It is often discovered incidentally in chest X-ray or chest CT scan performed for others reasons. We present here a case of pulmonary sclerosing pneumocytoma and discuss the clinical, histopathological features and treatment of this tumour in light of the data of the literature. Methods and Results:We report the case of pulmonary sclerosing pneumocytoma found in 66-year-old woman on chest CT scan performed for staging of a breast cancer. The patient underwent a left lower lobectomy and ipsilateral médiastinal lymph node dissection because frozen section examination suggested papillary adenocarcinoma. Conclusion:Most occurrences of pulmonary sclerosing pneumocytoma is often discovered incidentally. It is a rare benign tumour that frozen section examination is unable to diagnosis them in 25 to 56% of cases. The prognosis after surgical resection is excellent.

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“…PSH has been associated with increased FDG uptake and false positive results on 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT [8,11]. Lee et al [8] studied 8 patients with 10 PSHs and found that tumors larger than 2 cm can frequently be falsely interpreted as malignancy in FDG-PET/CT.…”

Section: Discussionmentioning

confidence: 99%

Synchronous occurrence of breast cancer and pulmonary sclerosing hemangioma: Management and review of the literature

Salemis

Seretis

Νάκος

et al. 2013

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Pulmonary sclerosing hemangioma (PSH) is a rare tumor accounting for 0.2-1% of all primary lung tumors. Simultaneous occurrence of PSH with breast cancer has very rarely been reported in the literature. We describe here a case of simultaneous occurrence of PSH with breast cancer. A pathological diagnosis of PSH was confirmed by computed tomography (CT)-guided biopsy. Due to the patient's poor performance status and the benign nature of PSH, surgical excision was not considered and the patient was managed conservatively with regular follow-up. Although surgical excision is the preferred treatment for PSH, conservative management may be a reasonable option in carefully selected patients.

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18F-FDG PET/CT features of pulmonary sclerosing hemangioma

Abstract: The majority of PSHs show increased FDG uptakes, and their SUVmax values are significantly correlated with their tumor size. PSH ≥2 cm can frequently be falsely interpreted as malignancy in FDG-PET/CT. Further studies with large study population are warranted to confirm our observations.

Cited by 31 publications

References 23 publications

18F‑FDG PET/CT characteristics of pulmonary sclerosing hemangioma vs. pulmonary hamartoma

18F‑FDG PET/CT characteristics of pulmonary sclerosing hemangioma vs. pulmonary hamartoma

Pulmonary Sclerosing Pneumocytoma: Case Report and Review of the Literature

Synchronous occurrence of breast cancer and pulmonary sclerosing hemangioma: Management and review of the literature

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