18F-FDG-PET/CT Findings of a Primary Hepatic Neuroendocrine Tumor: A Case Report and Literature Review

Abstract

Volume 5 -Issue 1 identified a location in the caudate lobe of the liver showing dilatation of the intrahepatic bile duct. The patient was then admitted to our hospital for a precise diagnosis and treatment. Sonographic imaging showed a solid hypoechoic lesion in the caudate lobe with an unclear boundary, a punctate blood flow signal, dilatation of the intrahepatic and extrahepatic bile duct, and right intrahepatic choledocholithiasis. No obvious abnormality was identified by either gastroscopy or colonoscopy. To determine the benign/malignant character of this lesion, a 18 F-FDG-PET/CT examination was performed. After six hours of fasting and one hour after the injection of 251.6 MBq of 18 F-FDG, the patient underwent a PET/CT examination using a dedicated scanner. The examination revealed a lesion measuring 5.8 cm × 6.2 cm in size with a CT value of 36.0 HU, indicating a mildly low density. The density of the parenchyma was homogenous, and the boundary was clear. PET imaging showed no 18 F-FDG uptake by the hypodense lesion first detected by CT imaging in the caudate lobe. Based on these symptoms, this case was defined as a primary

Primary hepatic neuroendocrine tumor

“…The degree of 18 F-FDG uptake on PET-CT was proportional to the Ki67 index. Grade 1 NETs with low Ki67 index values typically display hypometabolism, whereas grade 2 NETs can present with either hypermetabolism or hypometabolism (15). In the patient in our study, PET-CT with 18 F-FDG identified two lesions in the liver that were characterized by hypometabolism, and no other primary lesions were identified.…”

“…The application of PET-CT scans using 18 F-fluorodeoxyglucose ( 18 F-FDG) for PHNET assessment has been described in a few reports around the world (15). The degree of 18 F-FDG uptake on PET-CT was proportional to the Ki67 index.…”