18F-FDG PET-CT for Evaluation of Cardiac Angiosarcoma: A Case Report and Review of Literature

Abstract

Cardiac angiosarcomas are rare neoplasms. We here present the case of a 24 year old male with a cardiac mass which was characterised as malignant on 18F-Fluorodeoxyglucose (18F-FDG) positron emission tomography-computed tomography (PET-CT). In addition 18F-FDG PET-CT also demonstrated pericardial infiltration and bone metastases. The tumor was confirmed to be angiosarcoma on biopsy and palliative chemotherapy was started. Here we have highlighted the potential role of 18F-FDG PET-CT in patients with cardiac angiosarcoma and presented a brief review.

Primary cardiac angiosarcoma in multimodality imaging - Case report and review of literature

“…Úroveň a rozsah aktivity 18 F-FDG v myokardu může být heterogenní a variabilní, zvýšená fokální aktivita 18 F-FDG v myokardu může být způsobena myokardiální ischemií, ischemickou chorobou srdeční apod. [14]. Rovněž respirační pohyby mohou vést k nehomogenitě ve vychytávání 18 F-FDG v myokardu -zvýšení v laterálních a anteriorních oblastech a snížení v oblasti septa [14,15].…”

“…[14]. Rovněž respirační pohyby mohou vést k nehomogenitě ve vychytávání 18 F-FDG v myokardu -zvýšení v laterálních a anteriorních oblastech a snížení v oblasti septa [14,15]. Standardizovaná hodnota utilizace (SUV) je semikvantitativním ukazatelem utilizace 18 F-FDG (i jiných radiofarmak), jedná se o poměr mezi lokální objemovou aktivitou radiofarmaka a průměrnou objemovou aktivitou radiofarmaka v těle.…”

Molecular imaging of metastatic atrial angiosarcoma with positron emission tomography (PET) tracer 3′-deoxy-3′[(18)F]-fluorothymidine, [(18)F]-FLT imaging and early response evaluation

“…Arising from the vascular / lymphatic endothelial cells angiosarcomas are extremely rare neoplasms 1 2. They are highly aggressive neoplasms with a propensity to metastasise 1 3.…”

“…Arising from the vascular / lymphatic endothelial cells angiosarcomas are extremely rare neoplasms 1 2. They are highly aggressive neoplasms with a propensity to metastasise 1 3. Primary cardiac angiosarcoma, the most common primary cardiac sarcoma have an incidence ranging from 0.001% to 0.028% in autopsy reports with around 200 cases reported in literature 1 4 5.…”

“…They are highly aggressive neoplasms with a propensity to metastasise 1 3. Primary cardiac angiosarcoma, the most common primary cardiac sarcoma have an incidence ranging from 0.001% to 0.028% in autopsy reports with around 200 cases reported in literature 1 4 5. They are of mesenchymal origin.…”