[18F]FDG-PET/CT in different COVID-19 phases

Coronavirus Disease 2019 (COVID-19) in Molecular Imaging: A Systematic Review of Incidental Detection of SARS-CoV-2 Pneumonia on PET Studies

“…lung, corresponding to CT findings of subpleural GGOs in the dependent lung P45/M/70 Scarlattei 32 Italy Prostate cancer (adenocarcinoma) 18 F-choline Focal tracer uptake in a hilar, carinal, and peribranchial LN (SUVmax: 3.4) Mild focal tracer uptake (SUVmax: 3.8) was detected in in the subpleural region of both lungs and single GGOs localized in the middle lobe of the right lung P46/F/57 Scarlattei 32 Italy Focal Splenic lesions 18 F-FDG NR Intense/moderate uptake (SUVmax range: 4.6-3.7) in the bilateral subpleural regions corresponding to CT findings of GGOs in the posterior segments, with obvious extent in the Rt. lung P47/NR/NR Ajuria-Illarramendi 56 Spain Lung cancer 18 F-FDG NR Incidental 46-GGOs (with non-uniform density and air bronchogram), in the superior segment of the Rt. lower lobe with mild diffuse metabolic uptake (SUVmax: 3.9) P48/NR/NR Ajuria-Illarramendi 56 Spain Lung cancer 18 F-FDG NR Paramedial consolidation and thickened interlobular septa in the lower Rt.…”

“…lung P47/NR/NR Ajuria-Illarramendi 56 Spain Lung cancer 18 F-FDG NR Incidental 46-GGOs (with non-uniform density and air bronchogram), in the superior segment of the Rt. lower lobe with mild diffuse metabolic uptake (SUVmax: 3.9) P48/NR/NR Ajuria-Illarramendi 56 Spain Lung cancer 18 F-FDG NR Paramedial consolidation and thickened interlobular septa in the lower Rt. Lobe with high focal 18 F-FDG avidity (SUVmax: 5.3) suggesting severe infectious process P49/NR/NR Ajuria-Illarramendi 56 Spain Lung cancer 18 F-FDG NR Identified bibasal opacities with decreased density and fibrotic stripes which associate a heterogeneous high metabolic uptake (SUVmax:5) P50/M/67 Martineau 57 Canada Lung cancer (adenocarcinoma) 18 F-FDG Bilateral, hypermetabolic mediastinal lymphadenopathy, suggestive of reactive LN than metastatic disease relatively intense uptake (SUVs range:5.0-7.2) in the peripheral opacities, the patient lung nodule (SUV: 4.1) is seen in the right lower lobe P51/M/55 Zou 16 China Suggested hilar malignancy 18 F-FDG Increased accumulation of FDG was noted in the Rt.…”

Case Report: Incidental Finding of COVID-19 Infection after Positron Emission Tomography/CT Imaging in a Patient with a Diagnosis of Histoplasmosis and Recurring Fever

“… 15 The intensity of radiotracer uptake is described in a case report to be mild in the early phase of COVID-19 and higher in the acute severe and resolution phases. 16 However, more studies are necessary to analyze the pattern of the radiotracer uptake in the different phases of COVID-19 infection.…”

Effect of COVID-19 on18F-FDG PET/CT: Is There a Need to Consider COVID-19 Status Before Planning18F-FDG PET/CT for Oncologic Evaluation?

“…Various lung involvement patterns have been reported in 18 F-FDG PET/CT of COVID-19 patients undergoing workup for various malignancies. The patterns range from 18 F-FDG avid diffuse ground-glass opacities to 18 F-FDG avid patchy consolidatory changes, with or without 18 F-FDG avid mediastinal lymph nodes, depending on the imaging time from the onset of infection and other unknown factors [1][2][3][4]. COVID-19 infection was a retrospective diagnosis in most reported cases, after seeing the typical image findings in the 18 F-FDG PET/CT [3][4][5][6][7].…”