2012
DOI: 10.1002/jms.3071
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1912: a titanic year for mass spectrometry

Abstract: The 1912 sinking of the Titanic continues to capture the imagination and fascination of the general public. The year coincides with the birth of mass spectrometry that began with the cathode ray experiments performed by Joseph John (J. J.) Thomson in Cambridge. Modifications made to Thomson's cathode ray apparatus by Francis William Aston, resulted in an increase in the brightness of the positive rays that aided their detection. This led to the discovery of heavy isotopes for many of the chemical elements in t… Show more

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Cited by 3 publications
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“…Indeed, MS is a powerful tool thanks to accurate, specific and multiplex quantitation. These performances are due to the analysis of mass on charge (m/z) of ions from proteotypic peptides after sample ionisation 11 . In multiple reaction monitoring (MRM), at least three transitions, corresponding to the fragmentation of the precursor ion into products ions, are monitored 12 .…”
Section: Introductionmentioning
confidence: 99%
“…Indeed, MS is a powerful tool thanks to accurate, specific and multiplex quantitation. These performances are due to the analysis of mass on charge (m/z) of ions from proteotypic peptides after sample ionisation 11 . In multiple reaction monitoring (MRM), at least three transitions, corresponding to the fragmentation of the precursor ion into products ions, are monitored 12 .…”
Section: Introductionmentioning
confidence: 99%