1999-2010 yılları arasında kliniğimizde takip edilen herpes zoster olgularının retrospektif değerlendirilmesi

Abstract

Sum maryBackground and Design: Herpes zoster is a common viral disease of the nervous system. Although the annual incidence is 1.5-3/1000, this rate increases after 75 years of age. Seasonal factors are estimated to affect the incidence rate of the disease as well. The aim of this study was to investigate the clinical and demographic characteristics of patients diagnosed with herpes zoster and to explore the similarities and differences with other epidemiological studies from Turkey and the world.

Herpes Zoster Burden of Disease and Clinical Management in Turkey: A Comprehensive Literature Review

“…A third study reported the greatest proportion of HZ cases in summer (27.5%) and the lowest in autumn (22%) [ 34 ], and a fourth study noted that HZ cases were rare during winter and peaked in March (17.39%) [ 27 ]. Consistent with these data, Küçükçakır et al [ 28 ] reported that the highest number of HZ admissions occurred during summer in 1999–2010 (30.77%). However, one study of 100 patients with cancer reported that autumn (30%) and winter (30%) had the highest proportion of HZ cases [ 32 ].…”

“…Three studies were identified from independent dermatology clinics and one at an emergency department that reported the proportion of HZ cases among dermatological patients [ 26 – 29 ]. At the three dermatology clinics, the percentage of patients with HZ ranged from 0.43% in Van ( N = 115 from 2007 to 2010) [ 27 ], 0.56% in Düzce ( N = 312 from 1999 to 2010) [ 28 ], to 1.56% in Istanbul ( N = 3386; 2015–2016) [ 26 ]. A fourth study at an emergency department in Istanbul during 2016 reported that 1.17% ( N = 35) of dermatological patients had HZ, representing 0.02% of all emergency cases [ 29 ].…”

“…Another study, which investigated HZ infection in oncology patient records from 2009 to 2019 ( N = 100), reported that HZ was significantly more common in male patients (58%; p = 0.03) [ 32 ]. However, one retrospective study conducted in a pain clinic reported that 54% of HZ cases were female ( N = 200 from 2010 to 2019) [ 33 ], and two other retrospective studies reported close to equal proportions of male and female patients with HZ [ 28 , 34 ]. Likewise, the large retrospective VARICOMP study of patient records from eight Turkish centers ( N = 1955) reported almost equal proportions of male (48.4%) and female (51.6%) patients with HZ [ 35 ].…”

“…However, the proportion of patients who developed PHN varied substantially across independent studies. For example, Atiş et al (2017) reported that of 53 patients with HZ, 5.7% developed PHN, whereas Küçükçakır et al (2012) reported that 21.47% of 312 patients with HZ developed PHN [ 26 , 28 ], and a third, smaller retrospective study of 19 patients reported that 31.6% of patients developed PHN [ 53 ]. The highest proportion of patients with PHN was reported at a hospital in Bursa ( N = 90), where PHN developed in 58.8% of patients [ 55 ].…”