2,3-Dihydro-Quinazolin-4(1H)-One as a Fluorescent Sensor for Hg²⁺ Ion and its Docking Studies in Cancer Treatment

Abstract

The 2,3-dihydro-quinazolin-4(1H)-one was synthesised via the deployment of SBA-Pr-SO3H and its application was explored as a highly selective fluorescent sensor for Hg2+ ion; fluorescence intensity was decreased selectively by Hg2+ ions. Furthermore, this compound also indicated for its superb anti-interference ability among other ions. It is important to mention that this compound could be employed to detect a very low amount of Hg2+ ions, which are highly toxic and general contaminants. The docking study shows that the molecule, 2,3-dihydro-quinazolin-4(1H)-one, is a good inhibitor for the 5ACC enzyme.

Facile Green Synthesis of Cinnamomum tamala Extract Capped Silver Nanoparticles and its Biological Applications

“…The shift in band position in C. tamala extract and the Ag NPs clearly indicate that the biomolecules are involved in the reduction reaction with silver nitrate for Ag NPs formation. From the FTIR spectra of Ag NPs, it was clear that the formed nanoparticles were capped with the biomolecules, which stabilises them by preventing further agglomeration (this can be achieved by multiple supramolecular interactions [40]). It was mainly contributed by flavonoids, phenolics and tannins.…”