“…Due to the short period to scale up and the diversity production of secondary metabolites, fungi have become the new resource for natural products. The genus Daldinia belonging to the Xylariaceae is a genus of fungi that produces polyketide compounds with diverse structures and impressive biological activities, including immunosuppressive, cytotoxic, antiangiogenesis, anti-inflammatory, and antibacterial activities [ 1 , 2 , 5 , 6 , 7 , 8 ]. The two most investigated Daldinia species are D. eschscholtzii and D. concentrica which have produced many new compounds having remarkable biological activities including α -glucosidase inhibitory, antiangiogenesis, and anti-HIV activities [ 1 , 2 , 9 , 10 ].…”