2′-(4-Hydroxybenzylidene)isonicotinohydrazide monohydrate

Abstract

The bond lengths in the title compound, C13H11N3O2·H2O indicate that the organic mol­ecule exists in the keto form. A network of O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds helps to consolidate the crystal packing.

Crystal packing and theoretical analysis of halogen- and hydrogen-bonded hydrazones from pharmaceuticals. Evidence of type I and II halogen bonds in extended chains of dichloromethane

“…Here, the structural features of the hydroxyl analogue of IsI and IsBr are investigated. So far, two X-ray structures of N 0 -(4-hydroxybenzylidene)isonicotinohydrazide have been reported, namely in pure form (IsOH) and as the monohydrate (IsOHÁH 2 O) (Deng et al, 2005;Tai et al, 2007). In IsOH, molecules are superposed in a parallel displaced stacking and head-to-tail mode, with rather short OÁ Á ÁCe (pyridyl ring centre) and NÁ Á ÁCe (phenyl ring centre) distances of 3.298 and 3.449 Å , respectively (Fig.…”

Solid State Analysis and Theoretical Explorations on Polymorphic and Hydrate Forms of p-Hydroxybenzaldehyde Isonicotinichydrazone: Effect of Additives on Polymorphic Crystallization

“…Crystallization of HBIH molecules led to the formation of three different solid forms, which were governed by the employed conditions. Single crystals of PA were obtained by slow evaporation of the solution of p-hydroxybenzaldehyde isonicotinic acid hydrazone in methanol at 293 K. Forms PB and PC were reprepared by adopting different synthetic routes than their previously reported structures and therefore their crystal structures were redetermined by single-crystal X-ray diffraction to compare with the originally published structures [18,19]. All the crystallographic parameters are similar for the structures PB and PC.…”