2-[6-Alkyl-3-hetaryl-4-oxo-9,10-dihydro-4H,8H-chromeno-[8,7-e][1,3]oxazin-9-yl]acetic acids

Oxazine derivatives R 0595 2-[6-Alkyl-3-hetaryl-4-oxo-9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]oxazin--9-yl]acetic Acids. -The possibility of aminomethylating 3-hetarylchromones with formaldehyde and amino acids is investigated. Aminomethylation at position 8 of the chromone only occurrs in the case of glycine (III) and chromone (VIII) possessing an isoxazolyl moiety, whereas with other hetarylchromones acetic acid derivatives (IV) are formed. Similarly, reaction of chromone (Ia) with formaldehyde (II) and β-alanine (VI) affords the β-substituted propionic acid (VII). Proline does not participate in the interaction of two molecules of chromones (Ia) and (Ib) with a molecule of (II) furnishing bischromonylmethanes (V). -(GORBULENKO, N. V.; TKACHUK, T. M.; SHOKOL*, T. V.; SEMENIUCHENKO, V. V.; TUROV, A. V.; KHILYA, V. P.; Chem. Heterocycl. Compd. (N. Y.) 43 (2007) 5, 569-575; Taras Shevchenko Kiev Natl. Univ., Kiev 01033, Ukraine; Eng.) -H. Hoennerscheid 05-162

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ChemInform Abstract: 2‐[6‐Alkyl‐3‐hetaryl‐4‐oxo‐9,10‐dihydro‐4H,8H‐chromeno[8,7‐e] [1,3]oxazin‐9‐yl]acetic Acids.

Gorbulenko

Tkachuk

Shokol

et al. 2008

ChemInform

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An efficient synthesis of novel 11H-chromeno[3',2':3,4]pyrrolo-[2,1-b][1,3]thiazol-11-one heterocyclic system

Shokol

Gorbulenko

Khilya

2019

Chem Heterocycl Comp

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Synthesis and crystal structure poly[aqua(μ₃-2-(((7-hydroxy-3-(4-hydroxy-3-sulfonatophenyl)-4-oxo-4H-chromen-8-yl)methyl)ammonio)acetate-κ⁴ O,O′:O′′:O′′′) sodium] monohydrate, C₁₈H₁₈NNaO₁₁S

Chen

Lai

Qin

et al. 2018

Zeitschrift Für Kristallographie - New Crystal Structures

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2-[6-Alkyl-3-hetaryl-4-oxo-9,10-dihydro-4H,8H-chromeno-[8,7-e][1,3]oxazin-9-yl]acetic acids

Cited by 7 publications

References 7 publications

ChemInform Abstract: 2‐[6‐Alkyl‐3‐hetaryl‐4‐oxo‐9,10‐dihydro‐4H,8H‐chromeno[8,7‐e] [1,3]oxazin‐9‐yl]acetic Acids.

ChemInform Abstract: 2‐[6‐Alkyl‐3‐hetaryl‐4‐oxo‐9,10‐dihydro‐4H,8H‐chromeno[8,7‐e] [1,3]oxazin‐9‐yl]acetic Acids.

An efficient synthesis of novel 11H-chromeno[3',2':3,4]pyrrolo-[2,1-b][1,3]thiazol-11-one heterocyclic system

Synthesis and crystal structure poly[aqua(μ₃-2-(((7-hydroxy-3-(4-hydroxy-3-sulfonatophenyl)-4-oxo-4H-chromen-8-yl)methyl)ammonio)acetate-κ⁴ O,O′:O′′:O′′′) sodium] monohydrate, C₁₈H₁₈NNaO₁₁S

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2-[6-Alkyl-3-hetaryl-4-oxo-9,10-dihydro-4H,8H-chromeno-[8,7-e][1,3]oxazin-9-yl]acetic acids

Cited by 7 publications

References 7 publications

ChemInform Abstract: 2‐[6‐Alkyl‐3‐hetaryl‐4‐oxo‐9,10‐dihydro‐4H,8H‐chromeno[8,7‐e] [1,3]oxazin‐9‐yl]acetic Acids.

ChemInform Abstract: 2‐[6‐Alkyl‐3‐hetaryl‐4‐oxo‐9,10‐dihydro‐4H,8H‐chromeno[8,7‐e] [1,3]oxazin‐9‐yl]acetic Acids.

An efficient synthesis of novel 11H-chromeno[3',2':3,4]pyrrolo-[2,1-b][1,3]thiazol-11-one heterocyclic system

Synthesis and crystal structure poly[aqua(μ3-2-(((7-hydroxy-3-(4-hydroxy-3-sulfonatophenyl)-4-oxo-4H-chromen-8-yl)methyl)ammonio)acetate-κ4 O,O′:O′′:O′′′) sodium] monohydrate, C18H18NNaO11S

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Synthesis and crystal structure poly[aqua(μ₃-2-(((7-hydroxy-3-(4-hydroxy-3-sulfonatophenyl)-4-oxo-4H-chromen-8-yl)methyl)ammonio)acetate-κ⁴ O,O′:O′′:O′′′) sodium] monohydrate, C₁₈H₁₈NNaO₁₁S