2-(Benzoylamino)-3-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)acrylic acid

Abstract

A novel acrylic acid derivative was synthesized via acid hydrolysis of 4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-phenyloxazol-5(4H)-one in gl. acetic acid. The structure of the title compound was established on the basis of IR, 1H NMR, 13C-NMR and mass spectral data

5-[(5-Chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-2-(4-nitrobenzoyl)-3-phenyl-2,5-dihydro-1,2,4-triazin-6(1H)-one

“…The utilized azlactone was synthesized by the Erlenmeyer-Plochl method as discussed earlier [22]. The acid hydrazide was prepared from the acid via esterification followed by hydrazinolysis with hydrazine…”

N-[1-(1H-Benzimidazol-2-yl)-2-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)vinyl]benzamide

“…Erlenmeyer-Plochl azlactone synthesis was utilized for the synthesis of the azlactone from hippuric acid [12] and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde. The util;ized carboxaldehyde was in turn synthesized via Vilsmeier-Haack reaction.…”