2018
DOI: 10.1002/bkcs.11454
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2‐Bromo‐4,5‐Dimethoxy Chalcone Inhibits Cisplatin‐induced LLC‐PK1 Kidney Cell Death

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Cited by 2 publications
(1 citation statement)
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“…It consists of two aryl rings that are linked by α,β‐unsaturated ketone bridge which allow structural modification to design novel bioactive compounds. Its simple structure, low molecular weight, synthetic chemistry, and broad pharmacological importance such as anticancer, antioxidant, antibacterial, antifungal, antiviral, and anti‐inflammatory effect have increased scientific interest in the field of drug discovery. Many studies on natural, semi‐synthetic, and synthetic chalcone analogs have reported their significant anti‐inflammatory activity that inhibit potential targets, such as prostaglandins (PGs), lipoxygenase (LOX), cyclooxygenase (COX), interleukins (IL), leukotriene D 4 (LTD 4 ), and nitric oxide synthase (NOS) …”
Section: Introductionmentioning
confidence: 99%
“…It consists of two aryl rings that are linked by α,β‐unsaturated ketone bridge which allow structural modification to design novel bioactive compounds. Its simple structure, low molecular weight, synthetic chemistry, and broad pharmacological importance such as anticancer, antioxidant, antibacterial, antifungal, antiviral, and anti‐inflammatory effect have increased scientific interest in the field of drug discovery. Many studies on natural, semi‐synthetic, and synthetic chalcone analogs have reported their significant anti‐inflammatory activity that inhibit potential targets, such as prostaglandins (PGs), lipoxygenase (LOX), cyclooxygenase (COX), interleukins (IL), leukotriene D 4 (LTD 4 ), and nitric oxide synthase (NOS) …”
Section: Introductionmentioning
confidence: 99%