(2E)-1-(3-Chlorophenyl)-3-phenylprop-2-en-1-one

Abstract

In the title compound, C15H11ClO, the dihedral angle between the mean planes of the benzene ring and the chloro-substituted benzene ring is 48.8 (3)°. The dihedral angles between the mean plane of the prop-2-ene-1-one group and the mean planes of the 3-chloro­phenyl and benzene rings are 27.0 (4) and 27.9 (3)°, respectively. In the crystal, weak inter­molecular C—H⋯π-ring inter­actions occur.

New Pyrimidinone and Fused Pyrimidinone Derivatives as Potential Anticancer Chemotherapeutics

“…(2 E )‐1,3‐Bis(4‐chlorophenyl)‐2‐propen‐1‐one ( 1 ) was synthesized by the Claisen–Schmidt condensation method 28, which was performed with hydrogen peroxide in alkaline medium to produce (4‐chlorophenyl)[3‐(4‐chlorophenyl)oxiranyl] methanone ( 2 ) (Scheme ). Analytical and spectral data of compound 2 are in agreement with the proposed structure (cf.…”

“…Follow up of the reactions and checking the purity of the compounds was made by TLC on silica gel‐precoated aluminum sheets (Type 60 F254; Merck, Darmstadt, Germany). Compound 1 was prepared according to a reported method 28.…”

Spectroscopic, structural, thermal and antimicrobial studies of 4,6-bis (4-chlorophenyl)- 2-oxo-1,2-dihydropyridine-3-carbonitrile with some transition metals

“…The white precipitate was filtered off and dried under vacuum over anhydrous CaCl 2 . The light yellow, white and light green of [Fe(L) 2 4 .6H 2 O were prepared in similar manner described above by using acetone as a solvent and using Fe(NO 3 ) 3 .9H 2 O, CoCl 2 .6H 2 O and NiSO 4 .8H 2 O, respectively, in 1:2 molar ratio.…”

“…However, this procedure is time consuming and gives low yield. Jasinski et al [2,3] had reported an easy one-step synthesis which gives a higher yield of ligand by heating a mixture of 4-chloroacetophenone, 4-chlorobenzaldehyde, ethyl cyanoacetate and ammonium acetate in presence of glacial acetic acid as a catalyst.…”