(2S,4R)-1-Benzyl 2-tert-butyl 4-[N,N′-bis(tert-butyloxycarbonyl)hydrazino]-5-oxopyrrolidine-1,2-dicarboxylate

Abstract

Key indicatorsSingle-crystal X-ray study T = 293 K Mean (C-C) = 0.012 Å R factor = 0.052 wR factor = 0.158 Data-to-parameter ratio = 7.8For details of how these key indicators were automatically derived from the article, see

(2S,4R)-4-Ammonio-5-oxopyrrolidine-2-carboxylate

“…For the construction of modified amino acids, see: Dumy et al (1997); Keller et al (1998);Mutter et al (1999); Tuchscherer & Mutter (2001); Paul et al (1992). For pyroglutamic acid derivatives, see: Zabrocki et al (1988); Kaczmarek et al (2005). For the preparation of the title compound, see: Kaczmarek et al (2001); Kaczmarek (2009).…”

“…In contrast with a tetrazole replacement for the peptide bond, the pyroglutamic acid derivatives are more rigid (Zabrocki et al, 1988). Their carboxylic group could be either donor or acceptor of hydrogen bond without invloving the polypeptide main chain amide moieties (Kaczmarek et al, 2005).…”