(2-Methylthio-3-Pyridinecarboxylato)-diethyltin and -di-n-butyltin compounds: synthesis, spectroscopic characterization and in vitro antitumour activity. X-ray crystal structure of bis[diethyl(2-methylthio-3-Pyridinecarboxylato)tin] oxide and of diethyltin bis(2-methylthio-3-pyridinecarboxylate)

Synthesis, properties and crystal structural characterization of diorganotin(IV) derivatives of 2‐mercapto‐6‐nitrobenzothiazole

“…Crystal data for complex 1 Formula C 19 H 13 ClN 2 O 2 S 2 Sn, M = 519.57, triclinic, space group P1, a = 12.961(6), b = 13.835 (7), c = 16.412(8)Å, α = 69.184 (8) • , β = 89.862(9) Crystal data for complex 2 Formula C 28 Crystal data for complex 3 Formula C 22 …”

Synthesis, structural characterization and cytotoxic activity of organotin derivatives of indomethacin

“…However, in solution, such structures appear as four-coordinate species, because the oxygen atoms of the carboxylic group are non-coordinated to the tin atom. Dicarboxylatotetraorganodistannoxane dimers of the type {R COO(R 2 Sn)-O-(SnR 2 )OOCR } 2 have structural diversities in the crystalline state [13,15,16] and exhibit interesting biological activities…”

Syntheses, Characterizations, Crystal structures, and Antitumor Activities of Arenetelluronic Triorganotin Esters

“…Organotin complexes are an important branch of organometallics compounds and have received an on-going interest, largely because of their structural diversity [1][2][3] and particularly their potentially pharmic value [4][5][6]. Up to now, remarkable organotin derivatives such as carboxylates [7], phosphates [8], heterocyclic thioamides [9], and glycosides [10] have been isolated, and many of them were found to be active toward a number of tumor cells.…”

“…With these in mind, we are now interested in obtaining organotin complexes with organic telluronic acid ligands as a strategy for the preparation of new drug candidates in which the metal and the ligand could act synergistically. Herein, we report the syntheses and characterizations of six arenetelluronic triorganotin esters (R 3 Sn) 4 [ArTe(μ-O)(OH)O 2 )] 2 (Ar = Ph, R = Me: 1, R = Ph: 2; Ar = 3-Me-Ph, R = Me: 3, R = Ph: 4, Ar = 3-Cl-Ph, R = Me: 5, R = Ph: 6). Besides, the preliminary in vitro anticancer activity against two different cell lines, human lung carcinoma cell line (A549) and human colorectal cancer cell line (HCT-116), is also tested.…”