2-Oxo-2H-chromen-3-yl 4-tert-butylbenzoate

Abstract

In the title coumarin derivative, C20H18O4, the benzene ring of the benzoate group is oriented at a dihedral angle of 57.55 (9)° with respect to the planar chromene ring system [maximum deviation from plane is 0.027 (2) Å]. In the crystal, inversion-related molecules are linked into dimers via C—H...O hydrogen bonds, generating R 2 2(12) loops. The dimers are linked by further C—H...O hydrogen bonds forming layers, parallel to the bc plane, which are linked via C—H...π interactions, forming a three-dimensional framework

Overview of Recent Advances in 3-Hydroxycoumarin Chemistry as a Bioactive Heterocyclic Compound

“…This is the case for carboxylates of 4-hydroxycoumarin [40][41][42] and 7-hydroxycoumarin [43][44][45][46]. In the case of 3-hydroxycoumarin, the crystalline structure has been established for compounds 30b, 30c, 30d, 30e, 30g, 30j, 30h [6][7][47][48][49][50][51]. The crystallographic data are here reported for compound 30b, 30e, 30g, 30h.…”