2-Pyridone-based fluorophores: Synthesis and fluorescent properties of pyrrolo[3,4- c ]pyridine derivatives

De novogeneration of a bright blue fluorophore from 2-oxoglutarate in biological samples

“…The p-orbitals of the carboxylic acid and amide substituents may actively inuence the HOMO-LUMO levels, thereby changing the uorescence properties, as was similarly reported for other 2-pyridone-based uorophores. 9,10 In addition, we synthesized 2-pyridone derivatives with a fused g-lactam ring (5 and 6) using other synthetic processes. 11 Both compounds 5 and 6 show similar absorption and emission spectra to DTPP, and their quantum yields are enhanced up to 78-87%.…”

Oil-Dispersible Green-Emitting Carbon Dots: New Insights on a Facile and Efficient Synthesis

“…In particular, it is reasonable to assume that the blue emission is due to fluorescent species originating during the CPC carbonization, such as 2-pyridone derivatives of CPC. Indeed, 2-pyridones are a prominent class of fluorophores, well known, inter alia, as dyes, pigments or fluorescent bio-markers [ 52 , 53 ], which have been reported to form upon oxidation or disproportionation reactions, resulting from the treatment of pyridinium salts with NaOH under mild conditions [ 54 ]. In general, the formation, alongside the CDs, of blue-emitting molecular fluorophores has been largely demonstrated in popular CDs synthetic approaches based on the carbonization of citric acid in the presence of di- or triamines [ 26 , 27 , 28 , 29 , 30 , 31 ].…”

Exploiting a multicomponent domino reaction strategy for the tailoring of versatile environmentally sensitive fluorophore-based nicotinonitriles incorporating pyrene and fluorene moieties

“…The observed data also corroborates an assumption about the essential role of the cyano group in the pyridine ring causing the high uorescence of the pyridine derivatives and allows it to act as an excellent uorescent core with good electron-transporting properties. [46][47][48][49][50][51][52] It can be easily observed from the study that our nicotinonitrile-based uorescent type molecules containing pyrene and/or uorene moieties have been proven to be promising uorophores for application as chemo-and biosensors. Moreover, this type of structure with a highly electron decient system could be of interest to many researchers working on the development of n-type organic semiconductors and for the design of new liquid crystal materials.…”