2020
DOI: 10.31202/ecjse.824619
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2-Tiyofenasetik Asitten Türetilen Heterosiklik Amitler: Sentez, Karakterizasyon ve Antimikrobiyal Aktivitesinin Değerlendirilmesi

Abstract: Synthesized the heterocyclic amide derivatives (I-IV) were from 2-thiophene acetic acid in two steps. In the first step, the intermediate acylation agent formed and isolated, then subjected to aminolysis and obtained the corresponding amide derivatives. The structures of compounds obtained were characterized by FT-IR, 13 C NMR, 1 H NMR, spectroscopies and elemental analysis techniques. The antimicrobial activities of these four compounds against Gram-negative bacteria, Gram-positive bacteria and fungi were inv… Show more

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