Objective: To explore changes in the symptom clusters of elderly patients with lung cancer at different time points after surgery, and to analyze correlations between cluster severity, frailty and quality of life.
Methods: A longitudinal study was performed from August 2020 to June 2021 that included elderly patients with lung cancer who were operated upon at Jiangsu Province Hospital. Data were collected using the Chinese Tilburg Frailty Indicator, the MD Anderson Symptom Inventory and the Quality of Life-Core scale.
Results: According to exploratory factor analysis, a total of 5 symptom clusters were found and three of them (Global mental function symptom cluster, special mental function symptom cluster and respiratory function symptom cluster) were persistent. The incidence of the top four symptoms changed at different time points. The severity of symptom clusters at different time points was positively correlated with frailty and negatively correlated with quality of life.
Conclusions: Findings may provides a reference for medical staff to implement symptom management in elderly patients with lung cancer after surgery. Frailty may be an important variable affecting the severity of symptom cluster and quality of life of patients.