2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery

Hillis, L. David; Smith, Peter K.; Anderson, Jeffrey L.; Bittl, John A.; Bridges, Charles R.; Byrne, John G.; Cigarroa, Joaquin E.; DiSesa, Verdi J.; Hiratzka, Loren F.; Hutter, Adolph M.; Jessen, Michael E.; Keeley, Ellen C.; Lahey, Stephen J.; Lange, Richard A.; London, Martin J.; Mack, Michael J.; Patel, Manesh R.; Puskas, John D.; Sabik, Joseph F.; Selnes, Ola A.; Shahian, David M.; Trost, Jeffrey C.; Winniford, Michael D.; Jacobs, Alice K.; Albert, Nancy M.; Creager, Mark A.; Ettinger, Steven M.; Guyton, Robert A.; Halperin, Jonathan L.; Hochman, Judith S.; Kushner, Frederick G.; Ohman, E. Magnus; Stevenson, William G.; Yancy, Clyde W.; Holmes, David R.; Lewin, John C.; Wright, Janet; May, Charlene; Barrett, Erin A.; Bradfield, Lisa; Mukherjee, Debjani; Keller, Sue; Koinis, Maria; Sacco, Ralph L.; Brown, Nancy; Robertson, Rose Marie; Whitman, Gayle R.; Perkins, Cheryl L.

doi:10.1016/j.jacc.2011.08.009

Cited by 662 publications

(174 citation statements)

References 1,222 publications

(766 reference statements)

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“…To further study the importance of LVEF, we tested the multivariable model in patients without another indication for AVR, such as very severe AS defined as AV max ≥5 m/s or aortic valve mean gradient≥60 mm Hg, symptoms or positive stress test, LVEF<50%, or concomitant coronary revascularization indicated to improve survival. 10 The overall differences between models were tested by calculating the difference in log likelihood χ 2 between models that were based on the same set of patients. The assumptions (proportional hazard assumption, linearity of continuous variables, and lack of interaction) were tested and found valid.…”

Section: Discussionmentioning

confidence: 99%

Effect of Left Ventricular Ejection Fraction on Postoperative Outcome in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement

Dahl

Eleid

Michelena

et al. 2015

Circ: Cardiovascular Imaging

110

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Section: Discussionmentioning

confidence: 99%

Effect of Left Ventricular Ejection Fraction on Postoperative Outcome in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement

Dahl

Eleid

Michelena

et al. 2015

Circ: Cardiovascular Imaging

110

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“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Current guidelines, therefore, recommend surgical or transcatheter aortic valve replacement (AVR) for patients with severe symptomatic AS (class I). 19,20 Despite this fact, the optimal timing of intervention for patients with asymptomatic severe AS is uncertain and controversial.…”

Section: Introductionmentioning

confidence: 99%

“…5,[21][22][23][24][25][26][27][28][29] Since mortality rates are low for isolated surgical AVR (SAVR) and transcatheter AVR (TAVR), earlier intervention has been increasingly advocated. 14,15,[30][31][32] For asymptomatic patients, in particular, biomarkers may identify a subgroup of patients who would benefit from earlier valve replacement. Echocardiographic criteria of AS severity, based on anatomical and Doppler indices, have well-known limitations and can incorrectly classify as "moderate" AS patients with a more malignant AS phenotype who are at an increased risk of adverse events or rapid clinical AS progression.…”

Section: Introductionmentioning

confidence: 99%

Biomarkers in Aortic Stenosis: A Systematic Review

et al. 2017

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Aortic stenosis (AS) is one of the most common heart valve diseases among adults. When symptoms develop alongside severe AS, there is a poor prognosis unless aortic valve replacement (AVR) is performed; however, many patients do not report symptoms even when AS is severe. The optimal timing of AVR for these patients remains uncertain and controversial. AS is a heterogeneous disease with a complex pathophysiology involving structural and biological changes of the valve as well as adaptive and maladaptive compensatory changes in the myocardium and vasculature in response to chronic pressure overload. Several biomarkers reflecting these processes have been identified and have shown to have utility in predicting symptom onset and clinical events before and after AVR. Herein we systematically review biomarkers that have been studied in the setting of AS and summarize their potential use for risk stratification and ultimately to guide the optimal timing of AVR.

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“…Orthostatic hypotension thus seems to be a venous problem. Compared to Internal Thoracic Arteries (ITA) Human Saphenous Veins (HSV) demonstrate worse patency when used for Coronary Artery Bypass Grafting (CABG) [5,6]. After 10 years only about 50-60% of HSV grafts remain patent while patency for the ITA after 10 years is up to 96% [7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%