2013. Documento Sevilla de Consenso sobre Alternativas a la Transfusión de Sangre Alogénica. Actualización del Documento Sevilla

Leal-Noval, Santiago R.; Múñoz, Manuel; Asuero, M.; Contreras, Enric; García-Erce, José Antonio; Llau, Juan V.; Moral, V.; Páramo, José A.; Quintana, Manuel; Basora, M.; Paloma, Francisco Javier Bautista; Bisbe, E.; Bóveda, J.L.; Castillo-Muñoz, Álvaro; Colomina, M.J.; Fernández, C.; Mondéjar, E. Fernández; Ferrándiz, Carlos Colomer; Lorenzo, A. García de; Gomar, C.; Gómez-Luque, A.; Izuel, M.; Jiménez‐Yuste, Víctor; López-Briz, Eduardo; López‐Fernández, Macarena; Martín-Conde, J.A.; Ronsano, José Bruno Montoro; Paniagua, C.; Romero-Garrido, José Antonio; Ruiz, J.C.; Salinas-Argente, R.; Sánchez, Calixto; Torrabadella, P.; Arellano, Villa; Candela, A; Fernández, J.A.; Fernández-Hinojosa, Esteban; Puppo, Alessandro Del

doi:10.1016/j.redar.2012.12.003

Cited by 64 publications

(2 citation statements)

References 202 publications

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“…According to the most recent guidelines for GIB management, a restrictive transfusion strategy is recommended (Grade 1A), 4,25,26 with a Hb threshold value of 8 g/ dl 18,27 and 7 g/dl in patients with and without heart disease, respectively. 13,25 Moreover, it is currently recommended that patients with and without heart disease maintain a Hb target range of 8-10 g/dl and 7-9 g/dl after transfusion, respectively (Grade 1A), 18,25,27,28 even during active bleeding episodes (Grade 1C). 13 In this analysis is observed a post-transfusion global median Hb value 8,8 (IQR 7,9-9,6), according to the literature.…”

Section: Discussionmentioning

confidence: 99%

Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis

Costa

Pereira

Garção

et al. 2022

Clin Appl Thromb Hemost

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Acute upper or lower Gastrointestinal bleeding (GIB) is a clinical emergency in which transfusion can be lifesaving. An individualized and restrictive transfusion strategy is recommended. This study aims to analyze and evaluate GIB transfusion practices during one year in a large tertiary hospital in Lisbon, Portugal. All patients with GIB and transfusion support during 2014 were identified and clinical data collected and statistically treated. There were 1005 GIB transfusion episodes, in a total of 494 patients. Upper GIB was more common. The median haemoglobin concentration that triggered RBC transfusion was 7,6 g/dL with a median of 2 RBC per episode. In 21,9% of episodes, RBC were used in combination with other therapies, in 70,8%, only RBC were administered and in 7,3% RBC were not used at all. In the subgroup of patients receiving FC and/or PCC there were higher median of blood products transfused: RBC (3 17 units), FFP (3 units), PC (1 unit). In a large percentage of the transfusion episodes for GIB, only RBC were used whereas only 7,3% of the GIB didn't require RBC transfusion. Patients requiring FC and/or PCC, needed more allogenic components. We observed, in accordance with the latest clinical practice guidelines and the published literature, a restrictive transfusion approach in our clinical practice.

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Section: Discussionmentioning

confidence: 99%

Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis

Costa

Pereira

Garção

et al. 2022

Clin Appl Thromb Hemost

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“…[1][2][3] The therapeutic strategy for acute bleeding is mainly based on two approaches: (i) the use of predefined transfused ratios with variable combination of red cell concentrate, fresh frozen plasma and platelet concentrate (the ratio of 1:1:1 is usually associated with better outcomes) or (ii) the use of individualized goal-directed therapy, where different clusters of coagulation factors and pharmacological agents can be employed. [4][5][6][7][8] This last approach usually relies on close monitoring on clot formation and lyses by viscoelastic tests.…”

Section: Introductionmentioning

confidence: 99%

Portuguese Consensus and Recommendations for Acquired Coagulopathic Bleeding Management (CCBM)

Gomes¹,

Rodrigues

Carrilho

et al. 2021

Clin Appl Thromb Hemost

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We aimed to determine how Portuguese physicians handle major bleeding. We also aim to establish global diagnostic and therapeutic recommendations to be followed in clinical practice by using a step-wise approach of evidence generation. This study followed a three-step process: a steering committee desk review, a Delphi technique, an expert panel meeting. A modified 3-round Delphi including 31 statements was performed. Questions were answered in a five-point Likert-type scale. Consensus threshold was established as a percentage of agreement among participants ≥90% in the first round, and ≥85% in the second and third rounds. The level of consensus achieved by panelists was discussed with the scientific committee (January-2020). Fifty-one physicians participated in the study (compliance rate >90%). Analyzing the three rounds, consensus was reached on 20 items (64.5%) in the first, 4/11 items (36.4%) in the second and 6/7 items (85.7%) in the third. One statement about administration of clotting factor concentrates for bleeding control did not reach consensus. A high level of consensus was reached toward the need for implementing Patient Blood Management strategies in Portuguese hospitals, reduce exposure to allogeneic blood components, to use goal directed therapies for acquired bleeding management, and the need for evaluating blood transfusion indirect costs. A final version with 12 recommendations was built, according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Our results provide critically appraised and updated evidence on bleeding coagulopathies management in Portugal. Additional studies, mainly about indirect costs of blood transfusion, are needed.

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La anemia como factor de riesgo quirúrgico en cirugía vascular. Algoritmos de diagnóstico y tratamiento

et al. 2017

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2013. Documento Sevilla de Consenso sobre Alternativas a la Transfusión de Sangre Alogénica. Actualización del Documento Sevilla

Cited by 64 publications

References 202 publications

Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis

Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis

Portuguese Consensus and Recommendations for Acquired Coagulopathic Bleeding Management (CCBM)

La anemia como factor de riesgo quirúrgico en cirugía vascular. Algoritmos de diagnóstico y tratamiento

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