2021 Annual Report of the National Poison Data System
            <sup>©</sup>
            (NPDS) from America’s Poison Centers: 39th Annual Report

Gummin, David D; Mowry, James B.; Beuhler, Michael C.; Spyker, Daniel A.; Rivers, Laura J; Feldman, Ryan; Brown, Kaitlyn; Nathaniel, P T Pham; Bronstein, Alvin C.; Weber, Julie A

doi:10.1080/15563650.2022.2132768

Cited by 134 publications

(63 citation statements)

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“…Pastó et al described a similar proportion between men and women, suicidal intent was the principal motivation, and the mean age was 32 years (6). In the USA, psychoactive substance abuse (51.9%) has been described as the principal cause of poisoning, followed by suicidal intent in 23.6% (7). In a region of our country, a study identi ed that suicidal intent was 40.5% and a higher proportion of recreational use of psychoactive substances (26.6%), mainly in men (55.9%) and a median age of 23 years (8, 9).…”

Section: Discussionmentioning

confidence: 95%

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Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Hurtado,

Quintero,

Rodríguez

et al. 2023

Preprint

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Background Acute poisonings are a global public health problem, which implies costs and disease burden for society. In Colombia, there is a significant underreporting of data on acute poisoning and data gaps on the toxicological profile of the population. This study aims to identify the epidemiology of acute poisoning in a highly complex hospital in southwestern Colombia. Methods A descriptive study with retrospective data collection was performed. The variables were expressed through the measure of central tendency and dispersion. Categorical variables were described in proportions. Results A total of 406 patients were included. The median age was 31 years (IQR: 23–48), 56.2% were male, and only 19.2% had a history of mental illness. Suicidal intent represented 58.8% of the cases, and the most frequent route of exposure was the oral route (81.6%). The most prevalent groups of substances were pesticides (34.2%) and medicines (32%). The most common etiological agent was organophosphates (16.5%). Cholinergic toxidrome was the most common. The average stay in the ICU was 4.5 days (± 4.8), and the mortality was 4.2%. Conclusions The principal causes of acute poisoning were drugs and pesticides, with a predominant etiology of organophosphates and depressants of the central nervous system. There was a significant predominance of young male patients with suicidal intent, low mental disorders, elevated unemployment rate, and similar mortality reported in other studies. This study improves the knowledge about acute poisoning in southwestern Colombian to carry out multicenter analytics studies.

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Section: Discussionmentioning

confidence: 95%

“…The rst and second-level hospitals realized rst aid management, including decontamination measures in 39.4% (160 patients). In the United States, two studies described that the use of activated charcoal was 1.97% and 3.6%, gastric lavage 0.08% and 0.04%, and total intestinal irrigation 0.08 and 0.11% (7,19).…”

Section: Discussionmentioning

confidence: 99%

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Hurtado,

Quintero,

Rodríguez

et al. 2023

Preprint

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“…Similar data were obtained in a study carried out in China, where acute intoxications were mainly caused by sleeping pills (24.22%), analgesics (20.31%), and antipsychotics (16.41%) [ 9 ]. In Europe, as in the United States of America, the substances most associated with overdoses include analgesics drugs [ 8 , 10 ]. America’s Poison Centers report shows that in the last 10 years there has also been an increase in intoxications related to antidepressants (5.3%/year) [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

“…In Europe, as in the United States of America, the substances most associated with overdoses include analgesics drugs [ 8 , 10 ]. America’s Poison Centers report shows that in the last 10 years there has also been an increase in intoxications related to antidepressants (5.3%/year) [ 10 ]. However, data on fatal drug intoxication in Spain between 2000 and 2018 showed that in 2018, 72.6% of these intoxications were accidental and due to non-psychotropic/non-specified drugs.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Potential Intoxications with Medicines in a Regional Setting

et al. 2023

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The Portuguese Poison Information Center (from Portuguese—CIAV) is a call center that offers medical assistance in case of possible intoxication with any kind of product, including medicines. This center´s main goal is to inform and guide the general public and health professionals. This work aimed to analyze and compare data corresponding to the telephone calls from the Algarve region (South of Portugal), received by CIAV during 2019 and 2020, regarding potential intoxications with medicines. To this end, data provided by CIAV on possible cases of medication intoxication in the Algarve region were collected, including the number of calls received, the place of origin of the call, the age group and sex of the intoxicated individual, the route of exposure to the drug, the circumstances of contact with the substance, the existence of symptoms, and the drug or drugs involved in the potential intoxication. The results showed that the number of cases slightly decreased in 2020 (n = 1261) compared with 2019 (n = 1340), with a high number of cases of intoxication in children between one and four years old in both years (21.2%; n = 152 in 2019; 16.4%; n = 115 in 2020). The drugs belonging to the locomotor system group (paracetamol and ibuprofen) were the main drugs involved, followed by the central nervous system pharmacotherapeutic group, namely benzodiazepines (diazepam and alprazolam). Paracetamol was the main drug responsible for the calls to CIAV (n = 71 in 2019; n = 63 in 2020), while for the remaining drugs there were fluctuations in their positions between both years. In some cases, this swinging may be explained by the possible changes in therapy due to potential interactions with drugs used for the treatment of symptoms of COVID-19 or perhaps related to misleading information released by the media about the use of some drugs, such as ibuprofen, during lockdown periods. Although there has been a decrease in calls to report possible drug intoxication in the Algarve region, the profile of calls was very similar. Paracetamol was the drug with the highest number of reported cases and the group of psychotropic drugs showed the largest increase between 2019 and 2020.

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“…There are notable differences between the two national programs. PCs collectively manage 2.1 million potential poisoning consultations annually, over half of which involve children aged 19 years or younger [4]. By contrast, PEHSUs receive about 1200 consultation requests each year [5].…”

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confidence: 99%

Poison Centers and Pediatric Environmental Health Specialty Units: Productive Two-Way Partnerships

2023

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This year marks the 25th anniversary of the founding of the Pediatric Environmental Health Special Units (PEHSUs) program, created by the ATSDR and EPA in 1998 subsequent to President Bill Clinton's Executive Order 13045 [1]. It is now a collection of 10 regional PEHSUs forming a robust national network. This year also marks the 70th year anniversary of the founding of the poison centers (PCs) in Chicago, Illinois, in 1953 [2]. There is now a cohesive network of 55 regional PCs in the USA [3].These two national networks have largely operated independent of each other, with distinctly different missions but overlapping audiences. PEHSUs address clinical issues associated with environmental toxic hazards involving infants and children by offering clinical consultations, advanced training opportunities, and educational outreach efforts to the public, healthcare professionals, public health officials, and communities. In recent years, PEHSUs have expanded their scope of services to include issues in reproductive environmental health, the promotion of environmental justice for disadvantaged communities, and education around health consequences related to climate change.

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2021 Annual Report of the National Poison Data System ^© (NPDS) from America’s Poison Centers: 39th Annual Report

Cited by 134 publications

References 0 publications

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Characterization of Potential Intoxications with Medicines in a Regional Setting

Poison Centers and Pediatric Environmental Health Specialty Units: Productive Two-Way Partnerships

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2021 Annual Report of the National Poison Data System © (NPDS) from America’s Poison Centers: 39th Annual Report

Cited by 134 publications

References 0 publications

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Characterization of Potential Intoxications with Medicines in a Regional Setting

Poison Centers and Pediatric Environmental Health Specialty Units: Productive Two-Way Partnerships

Contact Info

Product

Resources

About

2021 Annual Report of the National Poison Data System ^© (NPDS) from America’s Poison Centers: 39th Annual Report