2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces

Wyckoff, Myra H.; Greif, Robert; Morley, Peter; Ng, Kee-Chong; Olasveengen, Theresa M.; Singletary, Eunice M.; Soar, Jasmeet; Cheng, Adam; Drennan, Ian R.; Liley, Helen; Scholefield, Barnaby R; Smyth, Michael A.; Welsford, Michelle; Zideman, David; Acworth, Jason; Aickin, Richard; Andersen, Lars W.; Atkins, Diane; Berry, David; Bhanji, Farhan; Bierens, Joost J.L.M.; Borra, Vere; Böttiger, Bernd W.; Bradley, Richard N; Bray, Janet; Breckwoldt, Jan; Callaway, Clifton W.; Carlson, Jestin N.; Cassan, Pascal; Castrèn, Maaret; Chang, Wei‐Tien; Charlton, Nathan P.; Chung, Sung Phil; Considine, Julie; Costa-Nobre, Daniela Testoni; Couper, Keith; Couto, Thomaz Bittencourt; Dainty, Katie N.; Davis, Peter G; Almeida, Maria Fernanda de; Caen, Allan R. de; Deakin, Charles D.; Djärv, Therese; Donnino, Michael W.; Douma, Matthew J.; Duff, Jonathan P.; Dunne, Cody; Eastwood, Kathryn; El-Naggar, Walid; Fabres, Jorge; Fawke, Joe; Finn, Judith; Foglia, Elizabeth E.; Folke, Fredrik; Gilfoyle, Elaine; Goolsby, Craig; Granfeldt, Asger; Guerguerian, Anne‐Marie; Guinsburg, Ruth; Hirsch, Karen G.; Holmberg, Mathias J.; Hosono, Shigeharu; Hsieh, Ming‐Ju; Hsu, Cindy H.; Ikeyama, Takanari; Isayama, Tetsuya; Johnson, Nicholas J.; Kapadia, Vishal; Kawakami, Mandira Daripa; Kim, Han-Suk; Kleinman, Monica E.; Kloeck, David; Kudenchuk, Peter J.; Lagina, Anthony T.; Lauridsen, Kasper Glerup; Lavonas, Eric J.; Lee, Henry; Lin, Yiqun; Lockey, Andrew; Maconochie, Ian; Madar, R. John; Hansen, Carolina Malta; Masterson, Siobhán; Matsuyama, Tasuku; McKinlay, Christopher J.D.; Meyrán, Daniel; Morgan, Patrick; Morrison, Laurie J.; Nadkarni, Vinay; Nakwa, Firdose; Nation, Kevin; Nehme, Ziad; Nemeth, Michael; Neumar, Robert W.; Nicholson, Tonia; Νικολάου, Νικόλαος; Nishiyama, Chika; Norii, Tatsuya; Nuthall, Gabrielle; O’Neill, Brian J.; Ong, Yong-Kwang Gene; Orkin, Aaron; Paiva, Edison Ferreira de; Parr, Michael J.; Patocka, Catherine; Pellegrino, Jeffrey L.; Perkins, Gavin D; Perlman, Jeffrey M.; Rabi, Yacov; Reis, Amélia G.; Reynolds, Joshua C.; Ristagno, Giuseppe; Rodrı́guez-Núñez, Antonio; Roehr, Charles C; Rüdiger, Mario; Sakamoto, Tetsuya; Sandroni, Claudio; Sawyer, Taylor; Schexnayder, Steve; Schmölzer, Georg M.; Schnaubelt, Sebastian; Semeraro, Federico; Skrifvars, Markus B.; Smith, Christopher M.; Sugiura, T.; Tijssen, Janice A.; Trevisanuto, Daniele; Voorde, Patrick Van de; Wang, Tzong-Luen; Weiner, Gary M.; Wyllie, Jonathan; Yang, Chih‐Wei; Yeung, Joyce; Nolan, Jerry P.; Berg, Katherine M.

doi:10.1016/j.resuscitation.2022.10.005

Cited by 56 publications

(15 citation statements)

References 369 publications

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“…35 Although current guidelines advocate normothermic temperature control (prevention of fever), it remains the opinion of many experts that there are subgroups of patients who may benefit from hypothermic temperature control. 36 The largest temperature control studies have focussed on OHCA patients with shockable rhythms and cardiac etiology. 25,26 A secondary analysis of the HYPERION study identified improved 90-day neurological outcomes among IHCA patients who were cooled to 33°C compared with normothermia (16.4% vs. 5.8%; P = 0.03).…”

Section: Unanswered Questions/future Researchmentioning

confidence: 99%

“…Although current guidelines advocate normothermic temperature control (prevention of fever), it remains the opinion of many experts that there are subgroups of patients who may benefit from hypothermic temperature control 36. The largest temperature control studies have focussed on OHCA patients with shockable rhythms and cardiac etiology 25,26.…”

Section: Unanswered Questions/future Researchmentioning

confidence: 99%

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Post-Cardiac Arrest Syndrome

Penketh

Nolan

2023

Journal of Neurosurgical Anesthesiology

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Post-cardiac arrest syndrome (PCAS) is a multicomponent entity affecting many who survive an initial period of resuscitation following cardiac arrest. This focussed review explores some of the strategies for mitigating the effects of PCAS following the return of spontaneous circulation. We consider the current evidence for controlled oxygenation, strategies for bloodpressure targets, the timing of coronary reperfusion, and the evidence for temperature control and treatment of seizures. Despite several large trials investigating specific strategies to improve outcomes after cardiac arrest, many questions remain unanswered. Results of some studies suggest that interventions may benefit specific subgroups of cardiac arrest patients, but the optimal timing and duration of many interventions remain unknown. The role of intracranial pressure monitoring has been the subject of only a few studies, and its benefits remain unclear. Research aimed at improving the management of PCAS is ongoing.

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Section: Unanswered Questions/future Researchmentioning

confidence: 99%

Section: Unanswered Questions/future Researchmentioning

confidence: 99%

Post-Cardiac Arrest Syndrome

Penketh

Nolan

2023

Journal of Neurosurgical Anesthesiology

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“…As of 2022, the International Liaison Committee on Resuscitation (ILCOR) suggests using the LMA as an alternative to the FM for performing PPV in the delivery room immediately after the birth of newborns >34 weeks’ gestational age, emphasizing the need of availability of resources and adequate training of healthcare professionals. 11 , 12 …”

Section: Introductionmentioning

confidence: 99%

Use of laryngeal mask for neonatal resuscitation in Brazil: A national survey

et al. 2023

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“…14,15 However, the reported values may not apply to infants who have deferred cord clamping (DCC), which is now the recommended standard care for vigorous term infants. 16…”

Section: Introductionmentioning

confidence: 99%

Blood Pressure and Cerebral Oxygenation with Physiologically-based Cord Clamping: A Sub-Study of the BabyDUCC Trial

Badurdeen,

Blank,

Hoq

et al. 2023

Preprint

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Background Cord-clamping strategies may modify blood pressure (BP) and cerebral tissue oxygen saturation (rStO2) immediately after birth. Methods We conducted a sub-study nested within the Baby-Directed Umbilical Cord-Clamping trial. Infants ≥32+0 weeks gestation assessed as requiring resuscitation were randomly allocated to either physiologically-based cord clamping (PBCC), where resuscitation commenced prior to umbilical cord clamping, or standard care where cord clamping occurred early (ECC). In this single-site sub-study, we obtained additional measurements of pre-ductal BP and rStO2. In a separate observational arm, non-randomised vigorous infants received 2 minutes of deferred cord clamping (DCC) and contributed data for reference percentiles. Results Among 161 included infants, n=55 were randomly allocated to PBCC (n= 30) or ECC (n= 25). The mean (SD) BP at 3-4 minutes after birth (primary outcome) in the PBCC group was 64 (10) mmHg compared to 62 (10) mmHg in the ECC group, mean difference 2 mmHg (95% confidence interval -3 to 8 mmHg, p= 0.42). BP and rStO2 were similar across both randomised arms and the observational arm (n=106). Conclusion We found no difference in BP or rStO2 with the different cord clamping strategies. We report reference ranges for BP and rStO2 for late-preterm and full-term infants receiving DCC.

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Cited by 56 publications

References 369 publications

Post-Cardiac Arrest Syndrome

Post-Cardiac Arrest Syndrome

Use of laryngeal mask for neonatal resuscitation in Brazil: A national survey

Blood Pressure and Cerebral Oxygenation with Physiologically-based Cord Clamping: A Sub-Study of the BabyDUCC Trial

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