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Abstract

return of spontaneous circulation (ROSC). In the primary analysis, mean DBP and max ETCO2 during the last 2 minutes prior to first shock were compared using receiver operating characteristic curves (area under curve (AUC)). In a secondary analysis, chest compression (CC) depth was compared to both DBP and ETCO2. Results: Survival was 19/30 (63%) animals (CPP20: 14/15 (93%); D51 5/15 (33%); p<0.01. hypoxic: 6/10 (60%); normoxic: 13/20 (65%); p=0.99). The optimal ROSC cut points were: DBP ≥ 26 mmHg (89% sensitive / 60% specific); ETCO2 ≥ 21 mmHg (89% sensitive / 27% specific). By AUC, mean DBP was superior to max ETCO2 (overall cohort: 0.86 vs. 0.37, p<0.01; hypoxic: 0.88 vs. 0.38, p<0.044; normoxic: 0.86 vs. 0.35, p<0.01), and both mean DBP (p<0.01) and ETCO2 (p=0.038) were superior to CC depth. Conclusions: In both hypoxic and normoxic models of VF, DBP was superior to ETCO2 in discriminating survivors from non-survivors, and both DBP and ETCO2 were superior to CC depth. ASYMMETRIC DIMETHYLARGININE, HOMOARGININE LEVELS AND ATRIAL FIBRILLATION IN OESOPHAGEC-TOMY PATIENTS.