2013
DOI: 10.1016/s0924-9338(13)77019-6
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2133 – Late-onset bipolar disorder: literature review and a case report of inaugural acute mania on an eldery woman with parkinson disease

Abstract: IntroductionRecent estimates suggest Bipolar disorder (BD) affects approximately 1% of the population, with diagnosis often made during late adolescence and early adulthood, and that it is lower in the elderly (up to 0.1%). The initial onset of BD generally presents with depressive episode, but an initial maniac episode is not uncommon, although it becomes less likely with increasing age. In spite of the fact that elderly is a growing population in developed countries there are only few studies on late-onset B… Show more

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(4 citation statements)
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“…Our study confirms epidemiological studies 35 , 36 , 37 , 38 , 39 , 40 , 41 and case reports 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 indicating that BSDs are associated with PD and suggests that BSDs may be a prodrome to PD, which is associated with a greater prevalence of psychiatric, somatoform, and cognitive complications; inadequate improvements after STN‐DBS; and higher mortality. High genetic susceptibility for BSD‐PD is suggested by the high prevalence of a family history of PD and BSD.…”
Section: Discussionsupporting
confidence: 92%
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“…Our study confirms epidemiological studies 35 , 36 , 37 , 38 , 39 , 40 , 41 and case reports 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 indicating that BSDs are associated with PD and suggests that BSDs may be a prodrome to PD, which is associated with a greater prevalence of psychiatric, somatoform, and cognitive complications; inadequate improvements after STN‐DBS; and higher mortality. High genetic susceptibility for BSD‐PD is suggested by the high prevalence of a family history of PD and BSD.…”
Section: Discussionsupporting
confidence: 92%
“…Earlier literature, instead, explicitly cited mania or hypomania among the possible complications of PD, addressing caveats 8,9 . Several case reports have indicated the prior occurrence or co‐occurrence of BSDs in PD patients 10‐28 . The 2006 international guidelines on subthalamic nucleus deep brain stimulation (STN‐DBS) 29 in PD, included hypomania as a preoperative concern, and more recent guidelines repeat the concern 30 .…”
mentioning
confidence: 99%
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