23 Utility Of Microcirculation Analysis in a Paediatric Animal Model of Hypovolemic Shock

Abstract

Background and aims Microcirculation assessment focus on 3 components: Vessel density, perfusion, and heterogeneity of microcirculation, measured as perfused vessel density (PVD), microcirculation flow index (MFI), proportion of perfused vessels and heterogeneity index (HI). Correlation of these parameters with hemodynamic and perfusion parameters is not well established. Methods Prospective, observational study in 17 two-month-old sedated, relaxed and mechanically ventilated piglets (8.6±1.1kg). Video sequences were recorded using Microscan Microvision® device at three different times: before, after induced hypovolemic shock and after fluid resuscitation. 51 sets of measurements where obtained by the analysis of video sequences using automated vascular analysis software. Microcirculation was assessed determining PVD, MFI and HI.