24-h pH-metry and Multichannel Intraluminal Impedance Monitoring in Obese Patients with and without Gastroesophageal Reflux Disease Symptoms

Abstract

Obese patients showed an increased number of refluxes with acid content. Refluxes with proximal extent were significantly higher in obese non-GERD than in controls and non-obese GERD patients. No difference was observed between the two obese patient groups. In asymptomatic obese patients, the WC correlated with proximal extent episodes.

Prevalence of gastroesophageal reflux disease in obese patients eligible for bariatric surgery

“…The prevalence of ERE in this same study was 18.7%, which was higher than that in the general population but lower than that in our sample (38.0%). 21 Similar to other studies, 5,21,27 our results showed a significant relationship (p=0.011) between BMI >35kg/m 2 and ERE. Furthermore, there was a significant correlation between ERE and the DeMeester score (p=0.028), and between ERE and transient LES relaxation (p=0.010), and the variables were strongly and positively correlated and varied simultaneously.…”

Gastroesophageal Reflux Affects Sleep Quality in Snoring Obese Children

“…According to our study, non-acid reflux does not play a role in the relationship between GER and sleep quality in obese children. This is consistent with the report that obese patients have more AGER and GERD but not non-acid reflux as compared to healthy volunteers [ 12 ]. Adult studies showed that a painful stimuli from acid reflux can be associated with arousals and brief awakenings as a protective mechanism, generating secondary peristalsis and facilitating acid clearance.…”

“…A higher prevalence of gastroesophageal reflux disease (GERD) and its complications have also been reported in obese patients [ 12 ]. The association of obesity and gastroesophageal reflux (GER) is reported with an odds ratio of 7.3 (95% CI 1.7-31.0) [ 13 14 15 ].…”

“Normal Values of 24H Multichannel Intraluminal Impedance pH-Metry in a Greek Obese Population Based on Montreal Definition of Gerd”

“…Only few studies exist in literature reporting data of the use of 24h MIIpH in obese individuals, but none of them reports normal values. A study from Ricci et al reported increased acid reflux episodes in obese symptomatic and asymptomatic individuals in comparison to non-obese healthy individuals [19]. Recently, Akyuz et al reported the results of 24h MIIpH in asymptomatic obese subjects revealing a positive correlation between BMI and the number of reflux episodes [20].…”