24-Hour profiles of salivary progesterone

Delfs, T.; Klein, Susann; Fottrell, P. F.; Naether, Olaf G.J.; Leidenberger, Freimut A.; Zimmermann, Ralf

doi:10.1016/s0015-0282(16)57058-7

Cited by 18 publications

(15 citation statements)

References 12 publications

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“…time of maximal concentration) of the E 2 diurnal rhythm is modulated by menstrual phases (Bao et al . 2003), studies on sex steroid secretion in normal cyclic women have suggested that E 2 and P 4 secretion exhibit a diurnal variation (Delfs et al . 1994, Bao et al .…”

Section: Introductionmentioning

confidence: 99%

Cortisol, estradiol-17β, and progesterone secretion within the first hour after awakening in women with regular menstrual cycles

Ahn¹,

Choi²,

Choi³

et al. 2011

Journal of Endocrinology

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Cortisol concentration in both serum and saliva sharply increases and reaches a peak within the first hour after waking in the morning. This phenomenon is known as the cortisol awakening response (CAR) and is used as an index of hypothalamus–pituitary–adrenal (HPA) axis function. We examined whether ovarian steroid concentrations increased after awakening as with the CAR in the HPA axis. To do this, cortisol, estradiol-17β (E2), and progesterone (P4) concentrations were determined in saliva samples collected immediately upon awakening and 30 and 60 min after awakening in women with regular menstrual cycles and postmenopausal women. We found that both E2 and P4 concentrations increased during the post-awakening period in women with regular menstrual cycles, but these phenomena were not seen in any postmenopausal women. The area under the E2 and P4 curve from the time interval immediately after awakening to 60 min after awakening (i.e. E2auc and P4auc) in women with regular menstrual cycles were greater than those in the postmenopausal women. E2 and P4 secretory activity during the post-awakening period was influenced by the phase of the menstrual cycle. E2auc in the peri-ovulatory phase and P4auc in the early to mid-luteal phase were greater than in the menstrual phase. Meanwhile, cortisol secretory activity during the post-awakening period was not influenced by menstrual status or the phase of menstrual cycle. These findings indicate that, as with the CAR in the HPA axis function, ovarian steroidogenic activity increased after awakening and is closely associated with menstrual status and phase of menstrual cycle.

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Section: Introductionmentioning

confidence: 99%

Cortisol, estradiol-17β, and progesterone secretion within the first hour after awakening in women with regular menstrual cycles

Ahn¹,

Choi²,

Choi³

et al. 2011

Journal of Endocrinology

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show abstract

“…Serum and salivary progesterone measurements have previously been shown to have similar pro®les in normal ovulatory cycles (Delfs et al, 1994), yet in those studies, the ratio of saliva to serum remain on average, less than 0´01. Metcalf et al (1984) noted preovulatory spikes of salivary progesterone when plasma levels were uniformly low, yet they assumed it was progesterone as it bound to progesterone antiserum.…”

Section: Discussionmentioning

confidence: 91%

“…Serum and salivary progesterone measurements have previously been shown to have similar profiles in normal ovulatory cycles ( Delfs et al ., 1994 ), yet in those studies, the ratio of saliva to serum remain on average, less than 0.01. Metcalf et al .…”

Section: Discussionmentioning

confidence: 99%

Salivary, but not serum or urinary levels of progesterone are elevated after topical application of progesterone cream to pre‐and postmenopausal women

O’Leary

Feddema

Chan

et al. 2000

Clinical Endocrinology

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“…An earlier study reported less freOnly two previous studies provide data on growth quent detection of EGF in BPH tissue compared to factors in PF. Tackett et al [9] [14]. Considered together, these results suggest a preparation of the manuscript.…”

Section: Introductionmentioning

confidence: 83%

“…In the normal prostate, EGF duced levels of EGF and TGF-ot in prostatic fluid could and TGF-ot appear to be apocrine secretory products, be explained by binding of these ligands to excess EGF with most immunostained material accumulating in receptor released by rapidly dividing cells [10]. ductal spaces [8,9]. With dysplasia and further proWe found only one previous study that compared gression to carcinoma, the normal cell polarity is lost growth factor levels in EPF across diagnostic groups.…”

Section: Sample Collection and Storagementioning

confidence: 99%

Developing New Epidemiologic Tools for Investigating Breast Cancer Risk

Gann¹

1999

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24-Hour profiles of salivary progesterone

Cited by 18 publications

References 12 publications

Cortisol, estradiol-17β, and progesterone secretion within the first hour after awakening in women with regular menstrual cycles

Cortisol, estradiol-17β, and progesterone secretion within the first hour after awakening in women with regular menstrual cycles

Salivary, but not serum or urinary levels of progesterone are elevated after topical application of progesterone cream to pre‐and postmenopausal women

Developing New Epidemiologic Tools for Investigating Breast Cancer Risk

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