2457. Multivariate Analyses of Socio-Economic Inequities in Parental Awareness and Utilization of Meningococcal Serogroup B Vaccines

Abstract

BackgroundIn 2015, the US Advisory Committee on Immunization Practices (ACIP) made a Category B recommendation for serogroup B meningococcal (MenB) vaccines for adolescents 16–18 years. In 2016, MenB caused ~60% of invasive meningococcal disease among US individuals 16–23 years old; however, utilization of MenB vaccines was much lower than other vaccines with Category A recommendations. Therefore, we examined factors associated with awareness and utilization of MenB vaccines.MethodsAn online quantitative survey was fielded among 619 US parents of adolescents aged 16–19 years, recruited from GfK’s KnowledgePanel® in December 2016. Demographics, access to care, decision making, and vaccine use were collected. A population-based weighting method was applied. Four logistic regressions and Classification And Regression Trees (CART) were conducted to examination most influential factors associated with MenB vaccine awareness and utilization.ResultsOf the weighted sample, 57% were unaware of MenB vaccines (Figure 1). Results from logistic regression models (Table 1) revealed that awareness was likely associated with gender and race. Parents who obtained a recommendation from HCPs were 4.8 (95% CI: 2.5–9.4) times more likely to vaccinate or intend to vaccinate their adolescent children and 5.7 (95% CI: 2.5–12.9) times more likely have adolescents already vaccinated than those parents who did not receive the recommendation from HCP. Race/ethnicity and insurance type were associated with awareness and vaccine utilization. The results from CART verified that HCPs’ recommendation is the most influential factor to predict the vaccination status. Parents’ socio-economic status and their relationship with HCPs were among the most influential predictors of awareness of MenB vaccines or interest in learning about MenB vaccines if they were unaware.ConclusionMenB awareness and vaccination are associated with parents’ socio-economic status and HCPs’ recommendation. Even among those unaware, there was a willingness to vaccinate when recommended by an HCP. These data underscore the critical need for robust understanding and consistent implementation of ACIP’s Category B recommendation to reduce inequities in MenB vaccine awareness and utilization. Disclosures L. Huang, Pfizer: Employee and Shareholder, Salary and Stocks. A. Dempsey, Pfizer, Merck: Scientific Advisor, Consulting fee. A. Galitsky, Pfizer: Collaborator, Research support. M. Fahimi, Pfizer: Collaborator, Research support. A. Srivastava, Pfizer: Employee and Shareholder, Salary.

Determinants of Meningococcal Vaccination Coverage and Adherence: A Targeted Literature Review Supporting a 16-year-old Healthcare Visit

“…For MenB vaccination, a survey of 619 US parents of 16–19-year-olds reported an HCP recommendation as the most influential factor in predicting MenB vaccination status [ 28 ]. Parents who received a recommendation from a provider were 4.8 times more likely to vaccinate their child and 5.7 times more likely to have an adolescent already vaccinated versus parents who did not receive a recommendation [ 30 ]. Finally, a survey of 445 parents of children attending high school in Minnesota reported that a top reason their child had not received a MenACWY or MenB vaccine was because their HCP did not recommend the vaccine (33.9% and 32.7%, respectively) [ 29 ].…”

Meningococcal vaccination: a discussion with all adolescents, whether college-bound or not

“…Additional recent US studies have reported this same association along the continuum of MenB vaccine awareness, intent to vaccinate, and receipt. A nationally representative survey of 619 parents of 16-19-year-olds demonstrated that awareness of MenB vaccines and interest in potentially vaccinating was significantly higher among those aware of MenACWY vaccines [17]. A regional cross-sectional survey of 445 parents of adolescents found that an equivalent percentage of parents were willing to vaccinate their teens with MenACWY and MenB vaccines (58.6% and 55.1%, respectively) and were seeking advice from their provider (79.6% and 81.1%) [18].…”