25036 Dermoscopic features of large cell acanthoma

Park, Jong Bin; Jung, Jang Hwan; Kwon, Do Ik; Seong, Seol Hwa; Suh, Kee Suck; Jang, Min Soo

doi:10.1016/j.jaad.2021.06.232

Cited by 2 publications

(2 citation statements)

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“…It is frequently described as a “stuck on” lesion on the neck and face including the eyelids, although it can also affect the extremities and trunk 28 . Skin‐colored or hypo‐pigmented variants are not infrequent 29 …”

Section: Pathogenesismentioning

confidence: 99%

Update of pathophysiology and treatment options of seborrheic keratosis

Gorai¹,

Ahmad

Raza

et al. 2022

Dermatologic Therapy

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Seborrheic keratosis (SK) is a common, benign tumor that can occur on everybody site and can be conservatively managed. Cosmetic concerns, especially when a lesion involves the facial area, are the most common reason for excision. SK shows male gender preponderance and increasing age is an independent association with the condition. Even though more prevalent in the elderly, it has also been reported in younger age groups like adolescents and young adults. Precise pathogenesis is still obscure, but ultra-violet exposure represents a predisposing factor to SK by altering the biochemical concentration and expression of factors like Glutamine deaminases, endothelin, and stem cell factor. Moreover, the accumulation of amyloid-associated protein has also been postulated. Involvement of genitalia has been associated with human papillomavirus infection. Recently, Merkel cell polyomavirus nucleic acid was also detected in SK. Several oncogenic mutations involving FGFR-3 and FOXN1 have been identified. SKs are usually classified clinically and histologically. Dermatoscopy is a noninvasive alternative diagnostic technique widely used in differentiating SK from other benign and malignant tumors. In terms of treatment, topical agents, shave dissection, cryosurgery, electrodesiccation, laser application and curettage under local anesthesia are safe methods for eradication of SKs, mostly for cosmetic purposes. Though generally safe, the latter techniques may occasionally cause postprocedure depigmentation, scarring, and recurrence. Nanosecond-pulsed electric field technology is a promising new technique with fewer side-effects.

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Section: Pathogenesismentioning

confidence: 99%

Update of pathophysiology and treatment options of seborrheic keratosis

Gorai¹,

Ahmad

Raza

et al. 2022

Dermatologic Therapy

View full text Add to dashboard Cite

show abstract

“…The most frequent dermoscopic findings are a yellow opaque homogenous area, grey/brown dots and globules, a moth-eaten border, white streaks, and a pseudonetwork 2,4 , most of which were also present in this case. Another study evaluated 13 patients and also identified these as the most frequent dermoscopic features and found that milia-like cysts and white to yellow surface scale were uncommon findings 5 . Therefore, dermoscopy is a noninvasive tool that can significantly aid in the diagnosis of LCA.…”

mentioning

confidence: 99%