259 Sinonasal Glomangiopericytoma: A Case Report of an Unusual Neoplasm With Emphasis on the Differential Diagnosis

Kassaby, Sarah; Patterson, Emily R.

doi:10.1093/ajcp/aqx123.258

Cited by 2 publications

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“…15 Major differential diagnosis of Hemangiopericytoma are lobular capillary hemangiomas, solitary fibrous tumours, leiomyomas, nasopharyngeal angiofibromas and glomus tumour. [16][17][18] Lobular capillary hemangioma (LCH) also called as pyogenic granuloma is a benign soft tissue tumour. Nasal septum is the common location of LCH involving the aerodigestive tract in 1/3 rd of cases.…”

Section: Discussionmentioning

confidence: 99%

Sinonasal haemangiopericytoma- An unusual swelling in the nasal cavity

Ahmed¹,

Talha²,

Warsi³

et al. 2020

IJOAS

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Sinonasal hemangiopericytoma, also known as glomangiopericytoma (GPC) is a benign perivascular tumor of low malignant potential, with an incidence rate of 0.5-1% of all sinonasal tumors. It often shows local recurrences with invasion to the surrounding bony tissues. It usually arises from the perivascular cells surrounding the capillaries. Etiology of the tumour is uncertain, with few postulated hypothesis like pregnancy, trauma, hypertension and corticosteroid drugs. They have an indolent course and tend to occur most commonly in the adults of seventh decade of life. We present a case report of 55 years old male presenting to the ENT OPD, with complaints of right sided nasal obstruction and repeated episodes of epistaxis since the last 9 months. History and general examination was unremarkable except for antihypertensive intake since the last few years. Laboratory investigations showed microcytic hypochromic anaemia, raised absolute eosinophil count of 1500 cells per microliter and positive Hepatitis B surface antigen (HBsAg) in the blood. Rhinoscopic examination showed a reddish brown nodular swelling in the right nasal cavity beneath the middle turbinate and hypertrophy of left nasal mucosa. CT imaging suggested an 18x15 mms, well defined soft tissue mass in the right nasal cavity. Complete resection of the mass with endoscopic surgery was performed. Histopathological examination coupled with immunohistochemistry confirmed the diagnosis of Sinonasal Hemangiopericytoma. This case report stresses upon various differential diagnosis of sinonasal swellings and the importance of considering long term follow up of Sinonasal Hemagiopericytoma.

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