25C-NBOMe – New potent hallucinogenic substance identified on the drug market

Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening

“…Of note, MS/MS spectra obtained from NBOMe derivatives using the CIT of the AI-MS 1.2 demonstrated much higher complexity compared to that contained in the Wiley Registry of Tandem MS Data (Supplementary Figure S-8C), although there have been similar reports in recent literature [28,68,69]. It has been asserted that the addition of the N-(2-methoxy)benzyl group to the 2C-phenethylamine structure (another electron donating aromatic ring, as seen in Supplementary Figure S-8C) creates more favorable sites for dissociation that can occur along the -C-C-N-C-linkage chain, specifically C-C bond cleavage between the α-and β-carbon atoms on the ethylene bridge [68,69].…”

Rapid Screening Method for New Psychoactive Substances of Forensic Interest: Electrochemistry and Analytical Determination of Phenethylamines Derivatives (NBOMe) via Cyclic and Differential Pulse Voltammetry

“…The DPV analysis was carried immediately by adding 50 L of the resulted mixture to the electrode. GC-MS method was adapted from previously described methods 7,24 . Cyclic Voltametry (CV) was performed using a potential range from -0.2 V to +1.4 V, step potential 0.01 V and scan rate 0.1 V/s.…”

“…Those compounds are potent agonists of the human 5HT2A receptor, responsible for subjective and behavioral effects 7,8 .They were mentioned for the first time in the book PIHKAL (1991) 9 . Although human consumption appears to have begun in 2010, it has increased rapidly as a consequence of the easy availability through the internet 5 .…”

PeakAL: Protons I Have Known and Loved - Fifty Shades of Grey-Market Spectra. Supplementary Data

“…data] In contrast, for a spectrum of 25C-NBOMe acquired in CDCl3 the overall splitting pattern is preserved but the ordering is not, becoming 6′, 4′, 5′, 3′. [51] Multiplets 3′ and 5′ have traded places. A ubiquitous, unanticipated peak at 8.15 ppm A characteristic peak was noted in the spectrum for 9 of the 10 N-benzyl analytes ( Figure 12).…”

“…[49] 1 H NMR spectra have been reported for 25B-NBOMe in DMSO-d6 [16,37] and in CDCl3 [15,50] ; for 25C-NBOMe in DMSO-d6, [37] in CDCl3, [51] and in CD3OD [16,52] ; for 25I-NBOMe in DMSO-d6, [16,37,53] in CDCl3, [15,[54][55][56] and in CD3OD [57] ; for 25I-NBOH in DMSO-d6 [15,16,37] ; for 25I-NBMD in DMSO-d6. [16,37] The 4-R family: 4-alkyl-2,5-dimethoxyphenyl pattern…”