2600 MHz Radiofrequency Radiation Exposure and Protective Role of Melatonin: Effects on Epididymis

Abstract

Objective: In this study, our aim is to investigate the possible protective effects of melatonin on potential damage caused by 2600 MHz radiofrequency (RF) radiation exposure on epididymis.Materials and Methods: 36 Wistar Albino male rats were divided into six groups. Group 1: Control, Group 2: Sham Control (mirror of RF exposure), Group 3: Sham Melatonin (mirror of RF exposure and melatonin injection), Group 4: Melatonin (melatonin injection), Group 5: RF (2600 MHz RF exposure), Group 6: RF and Melatonin (2600 MHz RF exposure and melatonin injection). During the experiment, body weights were measured and at the end of the 30-day experimental period, epididymis tissues were collected and examined with Hematoxylin-Eosin.Results: Epididymis was distinguished in normal histological appearance in the Control, Sham Control, Sham Melatonin and Melatonin groups. In the RF group, some structural degenerations were observed such as irregular tubule profile, deterioration and vacuolization in epithelium, loss of stereocilia, seperation in lateral and basal junctions of epithelium and immature sperm formation. In the RF and Melatonin group, the general histological appearance was found to be similar to the control groups except for some continuing degenerations. Conclusion:Taken together, 2600 MHz RF radiation exposure caused some structural degenerations on epididymis and melatonin administration provided therapeutic effects on these degenerations.

Non-Thermal Effect Of The Brand And Generic Mobile Phones Radiofrequency Radiation On The Antioxidant And Histomorphology Of The Epididymis After Prolonged Whole-Body Radiation on Sprague Dawley Rat

“…In this study, there were structural epithelial changes. However, no degenerative changes were observed in contrast to the study by Seymen et al (2021), which exposed male Wistar rats to 2600 MHz RF radiation for 30 days and reported structural degenerations in the epididymis such as irregular tubule profile, impairment and vacuolization of epithelium, loss of stereocilia, separation in lateral and basal junctions of epithelium and immature sperm formation. No differential degenerative histopathology changes between animals exposed to branded and generic mobile phone radiation.…”

Photoperiodic-dependent histomorphological changes in the excurrent duct system of helmeted guinea fowl subjected to short day (8L:16D), long-day (16L:8D) light/dark cycles and exogenous melatonin

“…Again, the exclusive observation of histoarchitectural distortion in the epithelium of distal efferent duct of guinea fowl exogenously administered melatonin (8 HL+ Mel) appeared to be surprising. As available reports on exogenous melatonin studies ( Seymen et al, 2021 ) have shown remarkable histo-architectural enhancement of the excurrent duct system. However, in the present study, this morphological distortion could be attributed to shorter duration of light exposure and exogeneous melatonin administration.…”