266 Evaluation of peri-partum supplementation of methionine hydroxy analog on cow-calf performance.

Redifer, Colby A; Tucker, H.A.; Loy, Daniel D.; Gunn, Patrick J.

doi:10.1093/jas/sky404.200

Cited by 4 publications

(3 citation statements)

References 236 publications

(366 reference statements)

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“…The increase in milk protein percentage and yield observed in this study in response to RPL and RPM agreed with what was previously obtained ( 9 , 14 , 16 , 61 , 62 ), but not always ( 27 , 63 , 64 ). Consistent with other studies, there was a positive response of dietary RPL and RPM supply on milk yield for transition and lactating and beef cows ( 13 , 14 , 16 , 61 , 65 , 66 ), but this response is not universal ( 12 , 27 , 67 – 69 ).…”

Section: Discussionsupporting

confidence: 89%

Feasibility of Supplying Ruminally Protected Lysine and Methionine to Periparturient Dairy Cows on the Efficiency of Subsequent Lactation

Elsaadawy

Wu²,

Bu³

2022

Front. Vet. Sci.

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The objective of this study was to evaluate the effects of supplying ruminally protected Lys (RPL) and ruminally protected Met (RPM) to transition cows' diets on the efficiency of subsequent lactation. A total of 120 prepartum Holstein cows were assigned into four treatments blocked by the anticipated calving date, previous lactation milk yield, number of lactations, and body condition score and fed either RPL, RPM, or the combination (RPML) or control diet (CON) throughout the transition period (3 weeks before till 3 weeks after calving). From 22 to 150 days in milk (DIM), all animals (100 cows) were fed a combination of RPM and RPL (0.17% RPM and 0.41% RPL of DM; n = 25 cows/treatment) as follows; CON–RPML, RPM–RPML, RPL–RPML, and RPML–RPML. Milk production and dry matter intake (DMI) were measured daily; milk and blood samples were taken at 21, 30, 60, 90, 120, and 150 DIM. Supplemented amino acids (AA) were mixed with the premix and added to the total mixed ration during the experiment. DMI (p < 0.001) and energy-corrected milk (ECM, p = 0.04) were higher for cows that were fed RPML–RPML than other cows. Compared with CON–RPML, yields of milk total protein, lactose, and nitrogen efficiency were increased (p < 0.01), whereas milk urea nitrogen (MUN; p = 0.002) was decreased for other treatments. However, supplemental AA did not affect milk lactose percentage, fat yield, feed efficiency, or serum total protein concentration (p > 0.10). Transition cows that consumed AA had a greater peak of milk yield (p < 0.01), as well as quickly reached the peak of milk (p < 0.004). There were differences in β-hydroxybutyrate concentration during the early lactation, with a lower level for AA groups (p < 0.05), and the difference faded with the progression of lactation (p > 0.10). Fertility efficiency as measured by pregnancy rate was improved by supplemental AA during the perinatal period (p < 0.05). In conclusion, transition cows consumed RPM and RPL, increased post-calving DMI, milk production, milk protein yield, nitrogen efficiency, and improved fertility performance.

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Section: Discussionsupporting

confidence: 89%

Feasibility of Supplying Ruminally Protected Lysine and Methionine to Periparturient Dairy Cows on the Efficiency of Subsequent Lactation

Elsaadawy

Wu²,

Bu³

2022

Front. Vet. Sci.

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“…Several studies have demonstrated increased milk yield with RPM or RPL supply during the transition period (16,19,33,62), in agreement with this study. Response to RPL has also been observed in later lactation cows (53,63), but this response is not universal (15,(64)(65)(66).…”

Section: Effects On Milk Production and Compositionmentioning

confidence: 98%

Supplementing Ruminally Protected Lysine, Methionine, or Combination Improved Milk Production in Transition Dairy Cows

Elsaadawy

Wang

et al. 2022

Front. Vet. Sci.

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The objectives of this study were to evaluate the effects of dietary supplementation of ruminally protected lysine (RPL), or methionine (RPM), and their combination (RPML) on the production efficiency of transition cows. A total of 120 pre-partum multiparous Holstein cows were assigned to four treatments based on previous lactation milk production, days (d) of pregnancy, lactation, and body condition score (BCS). Cows were fed a basal diet [pre-calving: 1.53 Mcal/kg dry matter (DM) and post-calving: 1.70 Mcal/kg DM] with or without supplemental ruminally protected amino acids (RPAA). Treatments were the basal diets without supplemental amino acids (CONTROL, n = 30), with supplemental methionine (RPM, pre-calving at 0.16% of DM and post-calving at 0.12% of DM, n = 30), with supplemental lysine (RPL, pre-calving at 0.33% of DM and post-calving at 0.24% DM, n = 30), and the combination (RPML, pre-calving at 0.16% RPM + 0.33% RPL of DM and post-calving at 0.12% RPM + 0.24 % RPL DM, n = 30). The dietary content of lysine was balanced to be within 6.157.2% metabolizable protein (MP)–lysine and that of methionine was balanced within 2.1–2.35% MP-methionine. Dry matter intake (DMI) was measured daily. Milk samples were taken on d 7, 14, and 21 days relative to calving (DRC), and milk yields were measured daily. Blood samples were taken on d −21, −14, −7 before expected calving and d 0, 7, 14, and 21 DRC. Data were analyzed using SAS software. There were significant Trt × time interactions (P < 0.01) for DMI pre- and post-calving period. The CON cows had lower DMI than RPM, RPL, and RPML, both pre-calving (P < 0.01) and post-calving periods (P < 0.01). Energy-corrected milk (P < 0.01), milk fat (P < 0.01), protein (P = 0.02), and lactose (P < 0.01) percentage levels were greater for RPM, RPL, and RPML cows compared to CON. Supplementing RPAA assisted in maintaining BCS post-calving than CON (P < 0.01). Blood concentrations of β-hydroxybutyrate decreased with RPM or RPL or the combination pre-calving (P < 0.01) and tended to decrease post-calving (P = 0.10). These results demonstrated that feeding RPL and RPM improved DMI and milk production efficiency, maintained BCS, and reduced β-hydroxybutyrate concentrations of transition cows.

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“…Many evidences point to increased bacterial protein synthesis, increased number of protozoa, increased fiber digestion, increased rumen fat synthesis, milk production, milk fat percentage, in lactating using MHA. Increases in milk production and milk fat percentage occurred mostly in early lactation cows and in herds using high percentages of concentration feed (9). But Results of using this product in other studies were variable.…”

Section: Introductionmentioning

confidence: 92%

Using Schiff base method for protecting amino acids and modified in vitro method for measuring rumen protected amino acids

Mazinani¹,

ِNaserian²,

Rude³

et al. 2021

IJVS

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266 Evaluation of peri-partum supplementation of methionine hydroxy analog on cow-calf performance.

Cited by 4 publications

References 236 publications

Feasibility of Supplying Ruminally Protected Lysine and Methionine to Periparturient Dairy Cows on the Efficiency of Subsequent Lactation

Feasibility of Supplying Ruminally Protected Lysine and Methionine to Periparturient Dairy Cows on the Efficiency of Subsequent Lactation

Supplementing Ruminally Protected Lysine, Methionine, or Combination Improved Milk Production in Transition Dairy Cows

Using Schiff base method for protecting amino acids and modified in vitro method for measuring rumen protected amino acids

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